Clinical Chemistry Panel Test Options

Test Code: RP60
CPT Code: 82607, 82728, 82746, 83540, 83550, 85025, 85045
Specimen: Serum and whole blood
Volume: 4 mL Serum and 7 mL whole blood
Container: Gel-barrier tube or transport tube and lavender-top (EDTA) tube, fill completely.
Collection: Follow instructions listed in individual test.
Storage and Stability: Maintain serum and EDTA whole blood at room temperature.

Tests Performed in Panel: CBC W/ Diff and RETICS | Test Code: RP41
Vitamin B12 | Test Code: RB08
Folate (Folic Acid) | Test Code: RB09
Ferritin 2 | Test Code: 1057
Total Iron | CPT Code: RL74
UIBC | CPT Code: 1126
TIBC | CPT Code: 1019

Use: This test is ordered to identify anemia and to diagnose the cause of anemia.
Test Code: RP48
CPT Code: 80053, 85025, 80061, 82306, 83540, 83550, 84144, 82627, 83003, 84436, 84479, 80076, 80069, 81002, 84402, 84403, 84550
Specimen: Whole blood (1 full tube), serum, urine
Volume: Whole blood (1 full lavender-top tube), urine (10 mL), serum (4 tubes completely filled)
Container: Lavender-top (EDTA) tube (for whole blood), gel-barrier (preferred) or red-top tube (for serum) and urinalysis tube or container, BD urine transport tube or sterile urine cup (for urinalysis)
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate

Tests Performed in Panel: Complete Metabolic Panel | Test Code: RP01
CBC with DIFF/PLAT | Test Code: RP04
Lipid Panel | Test Code: RP03
Vitamin D Panel 2 | Test Code: S057
Iron Profile | Test Code: RP31
Estrogen Panel | Test Code: RP11
Progesterone | Test Code: RL67
DHEA-Sulfate | Test Code: RL96
Growth Hormone | Test Code: 1124
Thyroid Panel2 | Test Code: RP20
Glucose | Test Code: RL01
Hepatic Function Panel | Test Code: RP18
Renal Function | Test Code: RP29
Urinalysis | Test Code: UA01
Testosterone Panel | Test Code: RP13
Uric Acid | Test Code: RL43

Use: This test is used for early detection, prevention, treatment and reversal of age-related diseases.
Special Request: 10-12 hours fasting required. Patient must avoid having radioisotope scan prior to collection of specimen.
Test Code: RP09
CPT Code: 80048
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred). Red-top tube or green-top tube is acceptable.

Collection: Patient should fast for 12 hours preceding collection of specimen. Draw blood in a gel-barrier tube and centrifuge. If red-top tube or green-top tube is used, centrifuge within 45 minutes of draw, remove the serum or plasma, and place in a transport tube and tightly stopper the tube.

Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Tests Performed in Panel: Glucose | Test Code: RL01
Blood Urea Nitrogen | Test Code: RL02
Creatinine | Test Code: RL03
BUN/Crea Ratio (Calc.)2 | Test Code: RL04
Sodium | Test Code: RL05
Potassium | Test Code: RL06
Chloride | Test Code: RL07
CO2 (Bicarbonate) | Test Code: RL08
Calcium | Test Code: RL09

Use: The test is used to check the status of a person's kidneys and their electrolyte and acid/bas balance, blood glucose level, which are related to a person's metabolism. The test can also be used to monitor people with certain known conditions, such as hypertension and hypokalemia, as well as hospitalized patients.

Special Request: Patient should fast for 12 hour preceding collection of specimen.
Test Code: RP49
CPT Code: 80061, 82306, 86141, 83090, 82172, 83525
Specimen: Serum (all other individual tests) or Plasma (Homocysteine)
Volume: 11 mL
Container: Gel-barrier tube
Collection: Separate serum or plasma from cells within 45 minutes of collection. Separate plasma or serum from cells immediately to avoid a false elevation of homocysteine.

Storage and Stability: Check individual tests

Tests Performed in Panel: Lipid Panel | Test Code: RP03
Vitamin D Panel | Test Code: S057
CRPHS | Test Code: 1038
Homocysteine, Blood | Test Code: B071
Apolipoprotein A-1 | Test Code: 1017
Apolipoprotein B | Test Code: 1018
Insulin | Test Code: 1125

Use: The panel is ordered to evaluate a person's cardiovascular related health factors.
Special Request: 10-12 hours fasting is required.
Test Code: RP04
Synonyms: Complete Blood Count with Differential
CPT Code: 85025
Specimen: Whole blood
Volume: Fill tube completely
Container: Lavender-top tube
Collection: Invert tube 8 to 10 times immediately after tube is filled at the time of collection.

Storage and Stability: Ship within 24 hrs after collection. Refrigerate. Do not Freeze.

Tests Performed in Panel: WBC | Test Code: RL25
RBC | Test Code: RL26
Hemoglobin | Test Code: RL27
Hematocrit | Test Code: RL28
MCV | Test Code: RL29
MCH | Test Code: RL30
MCHC | Test Code: RL31
PLT | Test Code: RL32
Seg Neutrophiles | Test Code: RL34
Lymphocytes | Test Code: RL35
Monocytes | Test Code: RL36
Eosinophils | Test Code: RL37
Basophils | Test Code: RL38
Neutrophil # | Test Code: RL62
Lymphocyte # | Test Code: RL63
Monocyte # | Test Code: RL64
Eosinophil # | Test Code: RL65
Basophil # | Test Code: RL66
RBC Distribution Width | Test Code: RB14
Mean Platelet Volume, MPV | Test Code: RB15

Use: The test is used as a screening test to evaluate overall health; detect and/or identify a wide range of hematologic disorders; assist in managing medications/chemotherapeutic decisions.
Test Code: RP40
Synonyms: Complete Blood Count without Differential, Hemogram
CPT Code: 85027
Specimen: Whole blood
Volume: Fill tube completely
Container: Lavender-top tube
Collection: Invert tube 8-10 times immediately after tube is filled at the time of collection.
Storage and Stability: Ship within 24 hrs after collection. Refrigerate. Do not Freeze.

Tests Performed in Panel: WBC | Test Code: RL25
RBC | Test Code: RL26
Hemoglobin | Test Code: RL27
Hematocrit | Test Code: RL28
MCV | Test Code: RL29
MCH | Test Code: RL30
MCHC | Test Code: RL31
PLT | Test Code: RL32

Use: The test is used as a screening test to evaluate overall health; detect, identify and or diagnose a wide range of hematologic disorders, such as anemia, infection, inflammation etc.
Test Code: RP41
Synonyms: Complete Blood Count with Reticulocyte count
CPT Code: 85045, 85025
Specimen: Whole blood
Volume: Fill tube completely
Container: Lavender-top tube
Collection: Invert tube 8-10 times immediately after tube is filled at the time of collection.
Storage and Stability: Ship within 24 hrs after collection. Refrigerate. Do not Freeze.

Tests Performed in Panel: WBC | Test Code: RL25
RBC | Test Code: RL26
Hemoglobin | Test Code: RL27
Hematocrit | Test Code: RL28
MCV | Test Code: RL29
MCH | Test Code: RL30
MCHC | Test Code: RL31
PLT | Test Code: RL32
% RETICULOCYTES | Test Code: 1129
RETICULOCYTES # | Test Code: 1130
MRV | Test Code: 1131
IRF | Test Code: 1132
NRBC | Test Code: 1133
NRBC # | Test Code: 1134
Seg Neutrophiles | Test Code: RL34
Lymphocytes | Test Code: RL35
Monocytes | Test Code: RL36
Eosinophils | Test Code: RL37
Basophils | Test Code: RL38
Neutrophil # | Test Code: RL62
Lymphocyte # | Test Code: RL63
Monocyte # | Test Code: RL64
Eosinophil # | Test Code: RL65
Basophil # | Test Code: RL66
RBC Distribution Width | Test Code: RB14
Mean Platelet Volume, MPV | Test Code: RB15

Use: This test is ordered as a screening test to evaluate overall health; detect, identify and or diagnose a wide range of hematologic disorders, such as anemia, infection, inflammation etc. It is also ordered to monitor bone marrow function after flow and/or function after treatments or marrow transplant.
Test Code: RP01
Synonyms:
CPT Code: 80053
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (send entire tube) is preferred. Red-top tube or green-top (heparin) tube is acceptable.

Collection: Draw blood in gel-barrier tube and centrifuge. If red-top tube or green-top tube is used, centrifuge within 45 minutes of draw, remove the serum or plasma, and place in a transport tube and tightly stopper the tube.

Storage and Stability: Room temperature. Stable for 3 days at room temperature/under frozen.

Tests Performed in Panel: Glucose | Test Code: RL01
Blood Urea Nitrogen | Test Code: RL02
Creatinine | Test Code: RL03
BUN/Crea Ratio (Calc.) | Test Code: RL04
Sodium | Test Code: RL05
Potassium | Test Code: RL06
Chloride | Test Code: RL07
CO2 (Bicarbonate) | Test Code: RL08
Calcium | Test Code: RL09
Total Protein | Test Code: RL10
Albumin | Test Code: RL11
Globulin | Test Code: RL12
A/G Ratio | Test Code: RL13
Alkaline Phosphatase | Test Code: RL14
AST (SGOT) | Test Code: RL15
ALT (SGPT) | Test Code: RL16
Bilirubin,Total | Test Code: RL17

Use: The test is used to evaluate a person's organ function and to check for some organ disease, such as diabetes, liver disease, and kidney disease.
Special request: Patient should fast for 12 hours preceding collection of specimen.
Test Code: RP70
Synonyms: Estimated Glomerular filtration rate
CPT Code: 82565
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Tests Performed in Panel: Creatinine | Test Code: RL03
eGFR If Non-African American | Test Code: RH08
eGFR If African American | Test Code: RH21

Use: The estimated glomerular filtration rate (eGFR) provides an assessment of the filtration capacity of the kidney. The test can be used to detect early kidney damage and to monitor kidney status. It is calculated from a serum creatinine using CKD EPI equation. Other factors, such as sex, age, race are needed for the calculation. The eGFR has been shown to be more accurate in estimating the glomerular filtration rate than a 24-hour urine collection for creatinine clearance. Among patients with chronic kidney disease (CKD), the eGFR is instrumental in determining the stage of disease according to the K/DOQI CKD classification.
Test Code: RP39
CPT Code: 80051
Specimen: Serum (preferred) or plasma
Volume: 2 mL

Container: Gel-barrier tube (send entire tube) preferred. Red-top tube or green-top (heparin) tube is acceptable if centrifuged within 45 minutes and the serum or plasma is removed and placed in a tightly-stoppered secondary tube.

Collection: Separate serum or plasma from cells within 45 minutes of collection; avoid hemolysis.
Storage and Stability: Room temperature. Stable for Specimen stable for 14 day under room temperature/refrigerated/frozen.

Tests Performed in Panel: Sodium | Test Code: RL05
Potassium | Test Code: RL06
Chloride | Test Code: RL07
CO2 | Test Code: RL08

Use: The test is used to identify an electrolyte, fluid, or pH imbalance. The test can be used to help diagnose conditions caused by electrolyte imbalance, such as dehydration, kidney disease, lung diseases, or heart conditions.
Test Code: RP11
CPT Code: 82670, 82677, 82679, 82672
Specimen: Serum
Volume: 5 mL
Container: Red-top tube, gel-barrier tube, or green-top (heparin) tube
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerated for 7 days

Tests Performed in Panel: Total Estrogens | Test Code: RL97
Estrone | Test Code: RL81
Estradiol | Test Code: RL99
Estriol | Test Code: RL76

Use: The panel is used to evaluate female sex hormone and sex hormone-related issues, such as fertility, placental function, etc.
Special request: Patient must avoid having radioisotope scan prior to collection of specimen.
Test Code: RP46
CPT Code: 82533, 82627, 82670, 82679, 84144, 84270, 84403
Specimen: Serum
Volume: 6 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerated

Tests Performed in Panel: DHEA-Sulfate | Test Code: RL96
Estradiol | Test Code: RL99
Estrone | Test Code: RL81
Progesterone | Test Code: RL67
Testosterone, Total | Test Code: RL92
SHBG | Test Code: RL93
Cortisol | Test Code: RL87

Use: This panel is used to check a women's hormone at different ages, especially pregnant women and women who enter the menopausal years.
Special request: 8-12 hour fast is required.
Test Code:
Synonyms:
CPT Code: 83001, 83002
Specimen:
Volume:
Container:
Collection:
Storage and Stability:
Tests Performed in Panel: Follicle-Stimulating Hormone (FSH) | CPT Code: 83001
Luteinizing Hormone (LH) | CPT Code: 83002

Use:
Test Code: RP18
Synonyms: Liver Function Panel
CPT Code: 80076
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or green-top (Heparin) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain Specimen at room temperature. Specimen stable for 2 days at room temperature, 3 days under refrigerated and 14 days under frozen.

Tests Performed in Panel: Albumin | Test Code: RL11
Alkaline Phosphatase | Test Code: RL14
ALT (SGPT) | Test Code: RL16
AST (SGOT) | Test Code: RL15
Bilirubin, Total | Test Code: RL17
Bilirubin, Direct | Test Code: RL40
Bilirubin, Indirect (Cal) | Test Code: RL41
Total Protein | Test Code: RL10

Use: The test is ordered to screen for liver damage, especially for someone on medications that have potential harmful to liver.
Test Code: RP19
CPT Code: 86677 (x3)
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 3 days at room temperature/refrigerated, 7 days under frozen.

Tests Performed in Panel: H. pylori Antibody IgG | Test Code: RH11
H. pylori Antibody IgA | Test Code: RH13
H. pylori Antibodies, IgM | Test Code: RH12

Use: Aid in the diagnosis of acute and chronic H pylori infections in patients with gastric and duodenal disease. Current studies suggest that H pylori IgM testing should be performed concomitantly with H pylori IgA and/or IgG tests for accurate diagnosis of Helicobacter pylori infection.
Test Code: RP77

Tests Performed in Panel: Immunoglobulin G (IgG) | Test Code: 1064
Immunoglobulin A (IgA) | Test Code: 1063
Immunoglobulin M (IgM) | Test Code: 1065
Total Protein | Test Code: RL10
Albumin | Test Code: RL11
Alpha-1-Globulin | Test Code: 1091
Alpha-2-Globulin | Test Code: 1092
Beta Globulin | Test Code: 1093
Gamma Globulin | Test Code: 1094
M-Spike | Test Code: 1095
Globulin | Test Code: RL12
A/G Ratio | Test Code: RL13

Test Code: RP31
CPT Code: 83540, 83550
Specimen: Serum (preferred) or plasma (lithium heparin only)
Volume: 2 mL
Container: Gel-barrier tube (preferred), transport tube or green-top (heparin) top tube. DO NOT use EDTA or oxalate anticoagulants.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days under room temperature/refrigerated/frozen.

Tests Performed in Panel: Total Iron | Test Code: RL74
UIBC | Test Code: 1126
TIBC | Test Code: 1019
% Iron Saturation | Test Code: 1010

Use: The test is used to help differential diagnosis of anemia, especially with hypochromia and/or low MCV. The test is also use to evaluate iron poisoning (toxicity) and overload in renal dialysis patients, or patients with transfusion dependent anemias.
Test Code: RP03
CPT Code: 80061
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier transport, green-top (heparin) tube, or lavender-top (EDTA) tube

Collection: Separate serum or plasma or from cells within 45 minutes of collection. Lipid panels are best avoided for three months following acute myocardial infarction, although cholesterol can be measured in the first 24 hours.

Storage and Stability: Storage and Stability: Refrigerate, Stable for 14 days

Tests Performed in Panel: Cholesterol, Total | Test Code: RL19
Triglycerides | Test Code: RL20
HDL Cholesterol | Test Code: RL21
LDL Cholesterol Calc | Test Code: RL22
CHOL/HDL Ratio | Test Code: RL23

Use: Evaluate hyperlipidemia as an index to coronary artery disease. The lipid profile is used as part of a cardiac risk assessment to help determine an individual's risk of heart disease and to help make decisions about what treatment may be best if there is borderline or high risk.
Test Code: RP17
CPT Code: See individual tests
Specimen: Serum (preferred) or plasma
Volume: 3 mL
Container: Red-top tube, gel-barrier tube, or green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Stable for 3 days.

Tests Performed in Panel: Blood Urea Nitrogen | Test Code: RL02
Calcium | Test Code: RL09
Total Protein | Test Code: RL10
Albumin | Test Code: RL11
Globulin | Test Code: RL12
A/G Ratio | Test Code: RL13
Alkaline Phosphatase | Test Code: RL14
AST (SGOT) | Test Code: RL15
ALT (SGPT) | Test Code: RL16
Bilirubin, Total | Test Code: RL17
Cholesterol, Total | Test Code: RL19
Triglycerides | Test Code: RL20
Phosphorus, Inorganic | Test Code: RL39
Bilirubin, Direct | Test Code: RL40
Bilirubin, Indirect (Cal) | Test Code: RL41
Gamma-Glutamyltransferase | Test Code: RL42
Uric Acid | Test Code: RL43
Lactate Dehydrogenase | Test Code: RL54

Use: Used to help diagnose liver disease if a person has signs and symptoms that indicate possible liver dysfunction. If a person has a known condition or liver disease, testing may be performed at intervals to monitor the health of the liver and to evaluate the effectiveness of any treatments.
Test Code: RP68
CPT Code: See individual tests
Specimen: Whole blood and Serum
Volume: (2) lavender top and (2) SSTs completely filled
Container: Lavender top tube (fill completely) and gel-barrier tube
Collection: If collected in red top tube, separate serum from cells after collection
Storage and Stability: Ship within 24 hrs for reliable results.

Tests Performed in Panel: Antinuclear Abs with Rfx | Test Code: R001
(P) CBC WITH DIFF/PLAT | Test Code: RP04
(P) COMPLETE METABOLIC PA | Test Code: RP01
Rheumatoid Factor | Test Code: RL48
ESR | Test Code: RL33
C-Reactive Protein, QL | Test Code: RL80

Use: Diagnosis of lupus can be challenging, especially because of its wide range of symptoms that may come on slowly and change over time. It is usually made by the clinical evaluation of physical signs and symptoms in combination with tests that can help to confirm the diagnosis or rule out other causes of a person's signs and symptoms.
Test Code: RP45
Synonyms: AFP Tetra, Alpha-Fetoprotein (AFP) Tetra Profile, Prenatal Quad Screen
CPT Code: 82105, 82677, 84702, 86336
Specimen: Serum
Volume: 5 mL
Container: Gel-barrier tube, no thrombin additive
Collection: Avoid hemolysis. Send complete specimen in the original tube. Do not pour off.
Storage and Stability: Refrigerate

Tests Performed in Panel: Maternal Serum AFP | Test Code: RP93
Estriol | Test Code: RL76
Inhibin A | Test Code: 1066
Beta HCG, Quantitative | Test Code: RL89

Use: AFP screening test for open neural tube defects (detects 80% open spina bifida, 90% anencephaly), Down syndrome (detects 75% to 80%), and trisomy 18 (detects 73%)

Special Instructions: The following information must be provided: gestational age, date on which the patient was the stated gestational age, how gestational age was determined (LMP, EDD, US), patient's weight, patient's date of birth, patient's race (white, black, other), and insulin-dependent diabetic status. Also indicate relevant patient history (e.g., prior neural tube defects, Down syndrome, ultrasound anomalies, or previous maternal serum screening specimen during this pregnancy). Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using The Maternal Prenatal Screening requisition form 0900. Specimens must be collected before amniocentesis.

Down syndrome screening is offered for gestational ages 15.0 to 21.9 weeks. Open spina bifida screening is offered for gestational ages 15.0 to 23.9 weeks. The optimal gestational age for open spina bifida screening is 16.0 to 18.9 weeks.

Estriol is used to evaluate fetal distress and placental function in the management of patients facing complications such as preeclampsia, fetal growth retardation, diabetes, Rh immunization, choriocarcinoma, and hydatidiform mole.

Inhibin A is used to access the function of the antral follicles the dominant follicle/corpus luteum of the ovaries in women.

Beta HCG test can be used for early detection of and on-going monitoring of pregnancy. Determine the presence of hCG in patients with gestational trophoblastic disease; evaluate and monitor male patients with testicular tumors; follow up molar pregnancy.
Test Code: RP42
Synonyms: Prostate Specific Antigen
CPT Code: 84153, 84154
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Maintain at room temperature

Room Temperature: 3 Days
Refrigerated: 3 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Tests Performed in Panel: PSA, Free | Test Code: RB10
PSA, Free Percent | Test Code: RB11
PSA, Total | Test Code: RL44

Use: The Prostate-Specific Antigen Best Practice Statement: 2009 Update published by the American Urologic Association describes the use of PSA testing for:

• The evaluation of men at risk for prostate cancer
• Assistance in pretreatment staging
• Risk assessment posttreatment monitoring
• Use as a guide in management of men who recur after primary or secondary therapy
Test Code: RP32
Synonyms: Prothrombin Time Assay, Protime, International normalized ratio
CPT Code: 85610
Specimen: Whole blood or plasma
Volume: 5 mL
Container: Blue-top (sodium citrate) tube; do not open tube unless plasma is to be frozen.

Collection: Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate.1 Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.2,3 The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.

Storage and Stability: Specimens are stable at room temperature for 24 hours. If testing cannot be completed within 24 hours, specimens should be centrifuged for at least 10 minutes at 1500xg; plasma should then be transferred frozen. Freeze immediately and maintain frozen until tested.

Tests Performed in Panel: Prothrombin Time (PT) | Test Code: RB01
INR | Test Code: RB12

Use: The prothrombin time (PT) is used, often along with a partial thromboplastin time (PTT), to help diagnose the cause of unexplained bleeding or inappropriate blood clots. The international normalized ratio (INR) is a calculation based on results of a PT and is used to monitor individuals who are being treated with the blood-thinning medication (anticoagulant) warfarin (Coumadin®).
Test Code: RP29
CPT Code: 80069
Specimen: Serum (preferred) or plasma
Volume: 4 mL
Container Red-top tube, gel-barrier tube, or green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Stable for 7 days. Refrigerate.

Tests Performed in Panel: Albumin | Test Code: RL11
Blood Urea Nitrogen | Test Code: RL02
Calcium | Test Code: RL09
Chloride | Test Code: RL07
CO2 (Bicarbonate) | Test Code: RL08
Creatinine | Test Code: RL03
Glucose | Test Code: RL01
Phosphorus, Inorganic | Test Code: RL39
Sodium | Test Code: RL05
Potassium | Test Code: RL06
BUN/Crea Ratio (Calc.) | Test Code: RL04

Use: To check renal function.
Test Code: RP33
CPT Code: See Individual tests
Specimen: Whole blood and Serum
Volume: Fill tubes completely
Container: Lavender top (1) and gel barrier tube (2)
Collection: Separate serum from cells within 45 minutes of collection
Storage and Stability: Ship within 24 hrs of collection for reliable results for CBC

Tests Performed in Panel: Rheumatoid Factor | Test Code: RL48
COMPLETE METABOLIC PANEL | Test Code: RP01
CBC WITH DIFF/PLAT | Test Code: RP04
C-Reactive Protein, QL | Test Code: RL80
ESR | Test Code: RL33
Antinuclear Abs with Rfx | Test Code: R001
CCP Antibodies | Test Code: 1144

Use: Primarily used to help diagnose rheumatoid arthritis (RA) and to help distinguish RA from other forms of arthritis or other conditions that cause similar symptoms.
Test Code: RP69
Synonyms: SLE
CPT Code(s): 86225; 86235(x5); 86431
Specimen: Serum
Volume: 5 mL
Container: Red-top tube or gel-barrier tube
Storage and Stability: Maintain specimen at room temperature, stable for 14 days

Tests Performed in Panel: RNP Antibodies | Test Code: 1158
Smith Antibodies | Test Code: 1159
RA Latex Turbid | Test Code: 1160
Antichromatin Antibodies | Test Code: 1161
Sjogren’s Anti-SS-A | Test Code: 1162
Sjogren’s Anti-SS-B | Test Code: 1163
Anti-DNA (DS) Antibody | Test Code: RL51

Use: Helps to diagnose systemic lupus erythematosus (SLE)
Test Code: RP43
CPT Code: See individual tests
Specimen: Serum
Volume: 5 mL
Container: Red-top tube or gel-barrier tube
Collection: If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate. Stable for 14 days.

Tests Performed in Panel: FSH | Test Code: RL83
LH | Test Code: RL84
Prolactin | Test Code: RL85
Testosterone, Total | Test Code: RL92
TSH | Test Code: RL18
Thyroxine (Total T4) | Test Code: RL90
Triiodothyronine T3 Total | Test Code: RH10

Use: See individual tests
Test Code: RP13
CPT Code: 84402, 84403
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days under room temperature/refrigerated/frozen.

Tests Performed in Panel: Testosterone, Total | Test Code: RL92

Use: The test is used to evaluate androgen excess or deficiency related to gonadal function, adrenal function, or tumor activity and to evaluate hirsutism and masculinization in women.
Test Code: RP34
CPT Code: 84443; If reflex testing is performed, concomitant CPT codes/charges will apply
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days under room temperature/refrigerated/frozen.

Tests Performed in Panel: TSH with Reflex | Test Code: 1056

Use: The test is used to aid clinicians in obtaining an appropriate diagnosis for common adult thyroid disorders. The cascade begins with a third-generation thyroid-stimulating hormone (TSH) test. If the TSH result is normal, a euthyroid status is assumed and testing stops. Additional testing is performed only if the initial TSH result is abnormally high or low. If TSH is < 0.450, it will reflex to thyroxine (T4), free, direct and depending on the thyroxine (T4), free, direct result, may reflex to a triiodothyronine (T3), free, both at an additional charge. If the TSH is > 4.500, it will reflex to thyroxine (T4), free, direct and depending on the thyroxine (T4), free, direct result, may reflex to a thyroid peroxidase (TPO) antibody, both at an additional charge.
Test Code: RP20
CPT Code(s): 84443, 84480, 84436, 84479
Specimen: Serum
Volume: 4 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate. Specimen stable for 14 days under room temperature/refrigerated/frozen.

Tests Performed in Panel: TSH | Test Code: RL18
Triiodothyronine T3 Total | Test Code: RH10
Thyroxine (Total T4) | Test Code: RL90
T3 Uptake | Test Code: RH18
Free Thyroxine Index | Test Code: RH19

Use: The test is used to evaluate a patient's thyroid function. The test is also used to help diagnose hypothyroidism and hyperthyroidism caused by various thyroid disorders.
Test Code: S047
Synonyms: Vitamin D, 25-Hydroxy, LC/MS-MS
CPT Code(s): 82306
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube.
Collection: If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.
Storage: Freeze. Stable at room temperature or refrigerated for seven days.
Stability: Stable at room temperature or refrigerated for seven days.

Tests Performed in Panel: 25 Hydroxy Vitamin D2 | Test Code: B080
25 Hydroxy Vitamin D3 | Test Code: B081
25 OH Vitamin D Total | Test Code: B082

Use: • Rule out vitamin D deficiency

• Determine if bone weakness, bone malformation, or abnormal metabolism of calcium (reflected by abnormal calcium, phosphorus, PTH) is occurring as a result of a deficiency or excess of vitamin D

• Help diagnose or monitor problems with parathyroid gland functioning since PTH is essential for vitamin D activation

• Screen people who are at high risk of deficiency, as recommended by the National Osteoporosis Foundation, the Institute of Medicine, and the Endocrine Society

• Help monitor the health status of individuals with diseases that interfere with fat absorption, such as cystic fibrosis and Crohn disease, since vitamin D is a fat-soluble vitamin and is absorbed from the intestine like a fat

• Monitor people who have had gastric bypass surgery and may not be able to absorb enough vitamin D
Test Code: RP47
CPT Code: 85025, 80051, 82533, 82627, 82670, 82679, 84144, 84270, 84403, 82746, 80076, 83540, 83550, 80061, 80069, 84436, 84479, 82607, 82306
Specimen: Whole blood (1 full tube) and serum
Volume: 1 full lavender-top tube and 15 mL of serum (3 SSTs filled completely)
Container: Lavender-top (for whole blood), gel-barrier tube (preferred for serum) or red-top tube.
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerated

Tests Performed in Panel: CBC WITH DIFF/PLAT | Test Code: RP04
VITAMIN D PANEL | Test Code: S057
THYROID PANEL | Test Code: RP20
LIPID PANEL | Test Code: RP03
HEPATIC FUNCTION PANEL | Test Code: RP18
RENAL FUNCTION | Test Code: RP29
IRON PROFILE | Test Code: RP31
ELECTROLYTE PANEL | Test Code: RP39
FEMALE HORMONE PANEL | Test Code: RP46
Folate (Folic Acid) | Test Code: RB09
Vitamin B12 | Test Code: RB08

Use: This panel is used to help evaluate a female's general health status.
Special request: 8-12 hour fast is required.
Test Code: RP50
CPT Code: See individual tests
Specimen: Whole blood and Serum
Volume: Fill tubes completely
Container: Lavender top tube (1) and gel-barrier tubes (2)
Collection: Separate serum from cells within 45 minutes of collection
Storage and Stability: Refrigerate and ship within 24 hrs of collection

Tests Performed in Panel: CBC WITH DIFF/PLAT | Test Code: RP04
LIPID PANEL | Test Code: RP03
COMPLETE METABOLIC PANEL | Test Code: RP01
TESTOSTERONE PANEL | Test Code: RP13
HEPATIC FUNCTION PANE | Test Code: RP18
THYROID PANEL | Test Code: RP20
PSA PANEL | Test Code: RP42

Use: Overall wellness checkup for males.



Clinical Chemistry Individual Test Options

A-Z | A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Test Code: 0342
Synonyms: 5-HIAA, 5-OH-Indoleacetic Acid, Serotonin Metabolite
CPT Code: 83497
Specimen: Urine (24-hour or random)
Volume: 5 mL
Container: Plastic urine container, no preservative (Note: 1 g/L boric acid may be added as a preservative for other tests without harm to 5-HIAA.)
Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.
Storage and Stability: Ambient temperature, Refrigerated, Frozen
Use: 5-HIAA is used to determine serotonin levels in the body and aid in the diagnosis of carcinoid syndrome. 5-HIAA levels can vary depending on other complications, including tumors, renal malfunction, and small bowel resection.

Special Instructions: Foods rich in indoles/serotonin (avocados, bananas, eggplant, pineapple, plums, tomatoes, walnuts) and medications that may affect metabolism of serotonin must be avoided at least 72 hours before and during collection of urine for HIAA. If possible patients should abstain from all medications, over-the-counter drugs, and herbal remedies (including coffee, tea, and tobacco) for at least 72 hours prior to the test.
Test Code: 6032 (Rh Factor: 6033)
Synonyms: Blood Type, Blood group
CPT Code: 86900
Specimen: Whole blood
Volume: 2 mL
Container: Lavender-top (EDTA) tube, pink-top (K2EDTA) tube, yellow-top ACD-A or ACD-B tube, or plain red-top tube
Collection: Refrigerate. Specimens should be tested as soon as possible or within 72 hours of collection. Samples that cannot be tested immediately should be stored at 2°C to 8°C.

Storage and Stability: Ambient temperature (3 days), Refrigerated (7 days), DO NOT FREEZE

Use: Determination of ABO blood group for transfusion candidates. Blood grouping of expectant mothers and newborns may indicate potential for ABO hemolytic disease of the fetus/newborn.
Test Code: 6030
Synonyms: ACTH, Corticotropin
CPT Code: 82024
Specimen: Plasma Frozen
Volume: 2 mL
Container: Plastic or siliconized glass lavender-top (EDTA) tube.
Collection: ACTH should be drawn between 7 AM and 10 AM. Collect into iced plastic or siliconized glass lavender-top (EDTA) tube, noting time of collection.

Storage and Stability: Freeze immediately

Use: Pituitary function test useful in the differential diagnosis of Cushing syndrome, ectopic ACTH syndrome (e.g. carcinoma of lung, islet cell tumors, carcinoid tumors, medullary carcinoma of thyroid), Addison disease, hypopituitarism, and ACTH-producing pituitary tumors (eg, Nelson syndrome).
Test Code: 1153
Synonyms: Aerobic Bacterial culture, Routine culture
CPT Code: 87070
Specimen: Pus or other material properly obtained from a body site (abscesses, eyes, tissue, wounds). Do not send syringe with needle.
Volume: Swab or 0.5 mL aseptically aspirated pus or tissue
Container: Sterile screw-cap container or bacterial swab transport; ESwab™ is acceptable
Collection: Disinfect contiguous areas of skin or mucous membrane containing resident normal flora prior to culture collection. Collect exudates from the interior of productive lesions. Tissue samples must be kept moist. A thin, air-dried smear for Gram stain obtained from the same site as the culture is strongly recommended (additional test).

Storage and Stability: Maintain specimen at room temperature

Use: Isolate and identify potentially pathogenic aerobic organisms. Susceptibility test is performed at additional charge when organisms isolated meet microbiologic criteria for clinical significance.

Special Request: Sterile preparation of the aspiration site is required.

The test request form must state specific site of specimen, age of patient, and time of collection. Inclusion of current antibiotic therapy and clinical diagnosis may aid the laboratory in evaluating the specimen and work-up of the culture. If an unusual organism is suspected, this information must be specifically noted on the test request form (eg, Nocardia) and may result in additional charges.

Specimens from other sources, such as genital, stool, urine, upper and lower respiratory specimens, cannot be cultured under the aerobic bacterial culture test number.
Test Code: RL16
Synonyms: ALT, SGPT
CPT Code: 84460
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, stable for 14 days.

Use: A liver function test, ALT is more sensitive for the detection of hepatocyte injury than for biliary obstruction. ALT is more specific for liver injury than AST (SGOT). Useful for hepatic cirrhosis, other liver disease. Increased in Reye syndrome, with AST.1 Test for hepatitis. Acute hepatitis A or B can be confirmed serologically, as can hepatitis C. Negative serological findings in the presence of hepatitis-like chemistry abnormalities may also suggest acute drug-induced hepatitis, an impression supported by resolution after removal of the offending agent.2 The combination of increased AST and ALT with negative hepatitis markers occurs in a number of other entities including infectious mononucleosis. Sensitive to heart failure.
Test Code: RL11
CPT Code: 82040
Specimen: Serum (preferred) or plasma
Volume: 1 mL
Minimum Volume: 5 ml
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, Stable for 14 days.
Use: Evaluation of nutritional status, blood oncotic pressure; evaluation of renal disease with proteinuria and other chronic diseases.
Test Code: RH01
CPT Code: 82088
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, Stable for 14 days.
Use: Evaluate patients with hypertension and possible hyperaldosteronism.
Test Code: RL14
Synonyms: Alkaline Phosphatase (ALP)
CPT Code: 84075
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection. If a red-top tube or green-top tube is used, transfer separated serum or plasma to a plastic transport tube.

Storage and Stability: Refrigerated, Stable for 14 days.
Use: The alkaline phosphatase test (ALP) is used to help detect liver disease or bone disorders.
Test Code: 1009
Synonyms: AFP, Alpha-Fetoprotein
CPT Code: 82105
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube
Collection: For a non-separator tube, transfer separated serum into a transport tube within 45 minutes of collection.
Storage and Stability: Ambient temperature (14 days), Refrigerated, Frozen

Use: AFP is useful to aid in the management of nonseminomatous testicular cancer when used in conjunction with information available from clinical evaluation and other diagnostic procedures. Elevated AFP concentrations have also been observed in ataxia telangiectasia, hereditary tyrosinemia, primary hepatocellular carcinoma, teratocarcinoma, gastrointestinal tract cancers with and without liver metastases, and in benign hepatic conditions such as acute viral hepatitis, chronic active hepatitis, and cirrhosis. The result alone cannot be interpreted as absolute evidence of the presence or absence of malignant disease. This test is not interpretable for tumor markers for pregnant females.
Test Code: 1039
Synonyms: AAG, α1-Acid Glycoprotein, A1AG, Orosomucoid
CPT Code: 82985
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube
Collection: For non-separator tube, transfer separated serum or plasma into a transport tube within 45 minutes of collection.
Storage and Stability: Refrigerated (14 days), Ambient temperature, Frozen
Use: Monitor acute-phase proteins associated with inflammatory conditions such as Rheumatoid arthritis and malignant neoplasms
Test Code: 1011
Synonyms: Acute Phase Proteins, Alpha1-Protease Inhibitor, AAT, A1A
CPT Code: 82103
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: For non-separator tube, transfer separated serum or plasma into a transport tube within 45 minutes of collection.
Storage and Stability: Ambient temperature (14 days), Refrigerated, Frozen

Use: The American Thoracic Society recommends AAT testing when individuals are diagnosed with certain conditions such as:

  • Emphysema at a young age (younger than 45 years old) and/or no obvious risk factors for the disease, such as smoking
  • Bronchiectasis, a condition in which the airways are stretched and/or widened
  • Asthma that is difficult to treat
  • Liver disease with no known cause
  • A skin disease called panniculitis, an uncommon complication of AAT deficiency that is characterized by red, tender nodules on the skin
Test Code: 1012 (peak), 1013 (trough)
Synonyms: Amikin®
CPT Code: 80150
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube.

Collection: Transfer separated serum or plasma to a plastic transport tube. Both peak and trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose. Peak samples should be drawn 60 minutes after an IM injection, 30 minutes after the end of a 30-minute IV infusion, or immediately after a 60-minute IV infusion.

Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/Frozen.
Use: Amikacin is used to treat serious infections caused by susceptible aerobic gram-negative bacilli. The test is ordered to monitor the level of the prescribed amikacin in the blood.
Test Code: 1100
CPT Code: 82150
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Stable for 14 days at room temperature/refrigerated/frozen.
Use: Amylase is used in the differential diagnosis of acute or chronic pancreatitis, which may or may not in an individual be related to alcoholism. Hypercalcemia related to pancreatitis is described with hyperparathyroidism and other entities.
Test Code: 1014
CPT Code: 82140
Specimen: Plasma, Frozen
Volume: 2 mL
Container: Lavender-top (EDTA) tube; EDTA is the only acceptable anticoagulant.

Collection: Tube must be filled completely and kept tightly stoppered at all times. Mix well. Specimen must be placed on ice immediately. Separate plasma from cells within 15 minutes of collection. Patient should not clench fist. Transfer specimen to a plastic transport tube before freezing. Avoid contamination of samples by ammonia from smoking or traffic in the laboratory or patient's room, glassware, or water. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage and Stability: Freeze. Ammonia is stable for several days at -20°C. Caution: Blood ammonia increases rapidly at room temperature.
Use: Ammonia measurements are mainly of use in the diagnosis of urea cycle deficiencies (any neonate with unexplained nausea, vomiting, or neurological deterioration appearing after first feeding), and they play an important part in the detection of Reye syndrome.

Special request: Patient should be fasting 12 to 14 hours to avoid lipemia, which interferes with the test.
Test Code: 1152
Synonyms: Anaerobic culture, Abscess; Anaerobic Culture, Body Fluid; Anaerobic Culture, Wound; Wound Anaerobic Culture
CPT Code: 87075
Specimen: Pus, tissue, or other material properly obtained from an abscess, biopsy, aspirate, drainage, exudate, lesion, or wound. To ensure proper growth of organisms place swabs/specimen in anaerobic transporter. Do not refrigerate.
Volume: Swab in anaerobic transporter, 0.5 mL pus, or other fluid or tissue from aspirated site in anaerobic transporter
Container: Anaerobic transport or aerobic/anaerobic bacterial swab transport containing gel medium.

Collection: Some anaerobes will be killed by contact with molecular oxygen for only a few seconds. Overlying and adjacent areas must be carefully disinfected to eliminate contamination with indigenous flora. Ideally, pus or other fluid obtained by needle aspiration through intact skin or mucosal surface that has been cleaned with antiseptic should be collected. Sampling of open lesions is enhanced by deep aspiration using a sterile plastic catheter. Curettings of base of an open lesion are optimal. If irrigation is necessary, nonbacteriostatic sterile normal saline may be used. Lower respiratory samples must be obtained by transtracheal percutaneous needle aspiration, transbronchial biopsy, transthoracic needle biopsy, or open lung biopsy by physicians trained in these procedures. If swabs must be used, collect two, use one for Gram stain and one for culture. Anaerobic transports must be used for swabs and for aspirates. Specimens are to be collected from a prepared site using sterile technique. Contamination with normal flora from skin, rectum, vaginal tract, or other body surfaces must be avoided.

Storage and Stability: Specimens for anaerobic culture should be maintained at room temperature. Under these conditions anaerobes will survive 24 to 72 hours when properly collected in the anaerobic transport tube.

Use: The only sources for specimens with established validity for meaningful anaerobic culture in patients with pleuropulmonary infections are blood, pleural fluid, transtracheal aspirates, transthoracic pulmonary aspirates, and specimens obtained at thoracotomy. Pleural fluid is preferred for patients with empyema. Blood cultures ¬¬yield positive results in < 5% of cases of anaerobic pulmonary infection. Specimens received in anaerobic transport containers are not optimal for aerobic fungus cultures. Mycobacterium sp or Nocardia sp, which may cause abscesses, will not be recovered even if present, since extended incubation periods, aerobic incubation, and special media are necessary for their isolation. Cultures for these organisms should be specifically requested, and a separate specimen submitted.

Test Code: RL98
Synonyms: 4-Androstenedione
CPT Code: 82157
Specimen: Serum
Volume: 2 mL
Container: Red-top tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the steroid by the gel. Depending on the specimen volume and storage time, the decrease in androstenedione level due to absorption may be clinically significant.

Collection: Transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: Androstenedione is used to evaluate the function of the adrenal gland and the ovaries or the testicles as well as the production of hormones related to the development of male sex organs and physical characteristics (androgens). It is most commonly used to determine the cause of symptoms of excess androgens in a woman who has an elevated testosterone level, along with a few other laboratory tests for this purpose.

Test Code: 1161
Synonyms: Antibodies to LE Cell Phenomenon
CPT Code: 86235
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If tube other than gel-barrier tube is used, transfer the separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.
Use: The test is used to help diagnose drug-induced lupus (DIL) and systemic lupus erythematosus (SLE).
Test Code: 1165
Synonyms: Anti-MPO Antibodies, PANCA-specific Antibody
CPT Code: 83520
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.

Use: For diagnosis and monitoring inflammatory activity in primary systemic small vessel vasculitides. The anti-MPO-ANCA EIA is useful for confirming positive ANCA results by IFA, particularly with the pANCA pattern.
Test Code: R001
Synonyms: Extractable Nuclear Antibodies, ANA-specific Antibodies
CPT Code: 86038
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube
Storage and Stability: Refrigerate, Stable for 14 days.

Use: The antinuclear antibody (ANA) test is used as a primary test to help evaluate a person for autoimmune disorders that affect many tissues and organs throughout the body (systemic) and is most often used as one of the tests to help diagnose systemic lupus erythematosus (SLE).
Test Code: 1016
Synonyms: ASO
CPT Code: 86060
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: This test is for detection of exposure to streptococcal streptolysin O.
Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.

Use: Document exposure to streptococcal streptolysin O. A marked rise in titer or a persistently elevated titer indicates that a Streptococcus infection or poststreptococcal sequelae are present.
Test Code: 1017
Synonyms: Alpha-Apolipoprotein, APO-A, A1-Apolipoprotein
CPT Code: 82172
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection. Patient must be fasting 12 to 14 hours.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: Apolipoprotein A-I (apo A-I) may be ordered, along with other lipid tests, as part of a profile to help determine a person's risk of developing cardiovascular disease (CVD). It may be used as an alternative to a high-density lipoprotein (HDL) test, but it is not generally considered "better" or more informative than HDL and is not ordered routinely.
Test Code: 1018
Synonyms: Beta Apolipoprotein
CPT Code: 82172
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection. Patient must be fasting 12 to 14 hours.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: The apolipoprotein B (Apo B) test is used, along with other lipid tests, to help determine an individual's risk of developing cardiovascular disease (CVD).
Test Code: RL15
Synonyms: Aspartate Aminotransferase; Serum Glutamic Oxaloacetic Transaminase; SGOT; Transaminases
CPT Code: 84450
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Stable at room temperature for 7 days, 14 days when refrigerated/frozen.

Use: The test is often ordered with other liver panel tests to detect and diagnose liver disorders. AST (SGOT) is affected by a wider range of diseases and organs.
Test Code: 1022
Synonyms: Beta-Microglobulin, Serum B2M
CPT Code: 82232
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or Red-top tube
Collection: For non-separator tube, transfer separated serum into a transport tube within 45 minutes of collection.
Storage and Stability: Ambient temperature (7 days), Refrigerated, Frozen

Use: This test is useful as an index of glomerular function and when ordered along with urine β-2 Microglobulin can be used to distinguish between glomerular and tubular dysfunction. Serum β-2 Microglobulin levels are a significant predictor of mortality in hemodialysis. Elevated levels are also noted in lymphproliferative disorders, neoplasms (malignant and benign), some renal disorders, inflammatory disease, and autoimmune diseases such as systemic lupus erythematosus (SLE) and Sjögren's disease.
Test Code: 1023
Synonyms: CO2
CPT Code: 82374
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (send entire tube) is preferred; red-top tube or green-top (heparin) tube is acceptable if centrifuged within 45 minutes and the serum or plasma is removed and placed in a tightly-stoppered secondary tube.

Collection: Draw blood in gel-barrier tube and centrifuge. If red-top tube or green-top tube is used, centrifuge within 45 minutes of draw, remove the serum or plasma, and place in a transport tube and tightly stopper the tube.

Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.
Use: The test is used to evaluate the total carbonate buffering system in the body, acid-base balance.
Test Code: RL17
CPT Code: 82247
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: A bilirubin test is used to detect an increased level in the blood. It may be used to help determine the cause of jaundice and/or help diagnose conditions such as liver disease, hemolytic anemia, and blockage of the bile ducts.
Test Code: 1122
Synonyms: Brain Natriuretic Peptide
CPT Code: 83880
Specimen: Plasma FROZEN
Volume: 2 mL
Container: Plastic Lavender-top (EDTA) tube.
Collection: DO NOT COLLECT IN GLASS. Collect in a plastic Lavender-top (EDTA) tube. Freeze within 24 hours and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage and Stability: Freeze

Use: Primarily used to help detect, diagnose, and evaluate the severity of heart failure. It can be used, along with other cardiac biomarker tests, to detect heart stress and damage and/or along with lung function tests to distinguish between causes of shortness of breath.
Test Code: RL02
Synonyms: Blood Urea Nitrogen
CPT Code: 84520
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube, green-top (lithium heparin) tube, or lavender-top (EDTA) tube; do not use ammonia heparin tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Room temperature
  • Room Temperature: 14 days
  • Refrigerated: 14 days
  • Frozen: 14 days
  • Freeze/thaw cycles: Stable x3
Tested as part of a routine comprehensive or basic metabolic panel; when you have signs and symptoms that may be due to kidney disease or you have a condition that may cause or be worsened by kidney dysfunction; at regular intervals when you are being treated for kidney disease or damage.

Use:

The blood urea nitrogen or BUN test is primarily used, along with the creatinine test, to evaluate kidney function in a wide range of circumstances, to help diagnose kidney disease, and to monitor people with acute or chronic kidney dysfunction or failure. It also may be used to evaluate a person's general health status when ordered as part of a renal panel, basic metabolic panel (BMP) or comprehensive metabolic panel (CMP).

Reference Ranges:

Age
Conventional Units2
SI Units3
0-18 years
Not available due to wide variability.
See child's lab report for reference range.
Adult
6-20 mg/dL
2.1-7.1 mmol/L
>60 years
8-23 mg/dL
2.9-8.2 mmol/L

1 from Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. 5th edition, St. Louis: Elsevier Saunders; 2011.
2 Conventional Units are typically used for reporting results in U.S. labs
3 SI Units are used to report lab results outside of the U.S.
Test Code: 1025
Synonyms: Cafcit®, Energets
CPT Code: 80155
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube.
Collection: Transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.
Use: Monitor caffeine concentration in newborns receiving theophylline or caffeine.
Test Code: RL09
Synonyms: Ca
CPT Code: 82310
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube; do not use oxalate, EDTA, or citrate plasma.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Room temperature. Stable for 14 days at room temperature/refrigerated/frozen.
Test: Current practices do not require fasting. You may be instructed to stop taking certain medications that can affect the test results, such as lithium, antacids, diuretics, and vitamin D supplements, among others:

Calcium can be used as a diagnostic test if a person has symptoms that suggest:
Use: Work-up for coma, pancreatitis and other gastrointestinal problems, nephrolithiasis, polydipsia, polyuria, azotemia, multiple endocrine adenomatosis.
References Ranges:
Age
Conventional Units
SI Units
Adult
8.6-10.2 mg/dL
2.15-2.55 mmol/L
Test Code: 1024
Synonyms: CA 15-3
CPT Code: 86300
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate, stable for 14 days.
Use: The test is ordered to quantitative measurement of cancer antigen 15-3.
Test Code: 1096
Synonyms: CA 27.29 Antigen, Truquant BR
CPT Code: 86300
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate. Stable for 5 days when refrigerated and more than 1 month when frozen.
Use: The test is used to manage patients with metastatic carcinoma of the breast.
Test Code: 1104
Synonyms: CA-125
CPT Code: 86304
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube (preferred)
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate
Use: Cancer Antigen 125 (CA-125) is a tumor marker primarily used to monitor therapy during treatment for ovarian cancer.
Test Code: 1061
Synonyms: Carbohydrate Antigen (CA) 19-9, Cancer Antigen 19-9
CPT Code: 86301
Specimen: Serum (preferred) or Plasma from green, lavender, or pink tube
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube
Collection: If red-top tube is used, transfer separated serum from cells into a plastic transport tube within 45 minutes of collection.
Storage and Stability: Ambient, Refrigerate, Frozen Stable for 14 days.

Use:
  • To help differentiate between cancer of the pancreas and other conditions, such as pancreatitis
  • To monitor response to pancreatic cancer treatment and/or cancer progression
  • To watch for pancreatic cancer recurrence
Test Code: 1144
Synonyms: Anti-CCP, Cyclic Citrullinated Peptide Antibodies
CPT Code: 86200
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: Following collection, Serum should be separated from the clot.
Storage and Stability: Room temperature. Stable for 7 days at room temperature, 14 days under refrigerated/frozen.
Use: This test is ordered along with other tests to help diagnose rheumatoid arthristis (RA).
Test Code: 1030
Synonyms: Carcinoembryonic Antigen
CPT Code: 82378
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preffered) or red-top tube
Collection: If a red-top tube is used, transfer separated serum transport tube.
Storage and Stability: Stable for 7 days at room temperature and 14 days under refrigerated/frozen.

Use: The test is used to determine the carcinoembryonic antigen in human serum or plasma. It can be ordered to monitor the treatment of people with colon cancer, may also be used as a marker for other cancers. It is also used to determine prognosis.
Test Code: 1031
CPT Code: 82390
Specimen: Serum (Preferred) or Plasma
Volume: 2 mL
Container: Gel-barrier tube (preffered), red-top tube or green-top (lithium heparin) tube.
Collection: Raw blood in gel-barrier tube (preferred). Separate serum or plasma from cells within 45 minutes of collection. Transfer separated serum or plasma to a plastic transport tube.

Storage and Stability: Refrigerate. Stable for 7 days at room temperature, 14 days if refrigerated or frozen.

Use: This test is used in evaluation of chronic active hepatitis, cirrhosis, and other liver disease. This test is also ordered along with blood and/or urine cooper test to help diagnose Wilson disease.
Test Code: RL07
Synonyms: Cl
CPT Code: 82435
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or green-top (lithium heparin) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Stable for 14 day at room temperature, refrigerated or frozen.
Use: The test is usually ordered along with other electrolyte tests to evaluate a person's electrolytes, acid-base balance, water balance.
Test Code: RL19
CPT Code: 82465
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Stable for 14 day at room temperature, refrigerated or frozen.
Use: The test is used to evaluate a person's lipid status and metabolic disorders.
Test Code: 1033
Synonyms: Pseudocholinesterase
CPT Code: 82480
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.
Collection: Separate serum from cells immediately after clotting (30 minutes) and place in transport tube. Mark transport tube "serum".
Storage and Stability: Room temperature. Stable for 14 days under room temperature/refrigerated/frozen.

Use: The test is used to evaluate preoperative patients for succinylcholine (suxamethonium) anesthetic sensitivity, genetic or secondary to insecticide exposure, in appropriate circumstances. To prevent or evaluate prolonged anesthetic effect, prolonged apnea, after surgery. Very small amounts (0.04−0.06 mg/kg) of succinylcholine are needed to obtain 90% of neuromuscular blockade in patients with low levels of plasma cholinesterase activity.
Test Code: 1035
Synonyms: C3, C3 (β1C/β1A Globulin), C3 Complement
CPT Code: 86160
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube or green-top (heparin) tube.
Collection: Remove serum or plasma within 45 minutes and transfer to a plastic transport tube.
Storage and Stability: Refrigerated. Stable for 2 day at room temperature, 3 days under refrigerated and 7 days under frozen.

Use: The test is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom complement is consumed at an increased rate. These include lupus erythematosus, chronic active hepatitis, certain chronic infections, poststreptococcal and membranoproliferative glomerulonephritis, and others.
Test Code: 1036
Synonyms: C4, C3 (β1e Globulin), C4 Complement
CPT Code: 86160
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube or lavender-top (K3-EDTA).
Collection: Allow serum to clot at room temperature for 15 to 30 minutes. Remove serum or plasma after centrifugation and transfer to a plastic transport tube.
Storage and Stability: Maintain specimen at room temperature. Stable for 3 days at room temperature/under refrigerated and 14 days under frozen.

Use: The test is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom complement is consumed at an increased rate. These include lupus erythematosus, chronic active hepatitis, certain chronic infections, poststreptococcal and membranoproliferative glomerulonephritis, and others.
Test Code: RL87
Synonyms: Hydrocortisone, Compound F
CPT Code: 82533
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. Blood should be drawn at 8 AM and 4 PM to evaluate baseline diurnal variation.
Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Use: This test is used to help diagnose hypercortisolism disease (also known as Cushing syndrome) or cortisol deficient related diseases, such as adrenal insufficiency or Addison disease.
Test Code: RL03
CPT Code: 82565
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, green-top (heparin) tube, or lavender-top tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Use: A renal function test used in eGFR calculation. It is used along with other renal function test (usually blood urea nitrogen test) to evaluate kidney function.

Reference Ranges:
18-60 years
   
Male
0.9 - 1.3 mg/dL
80 - 115 µmol/L
Female
0.6 - 1.1 mg/dL
53 - 97 µmol/L
60-90 years
   
Male
0.8 - 1.3 mg/dL
71 - 115 µmol/L
Female
0.6 - 1.2 mg/dL
53 - 106 µmol/L
Test Code: RL55
Synonyms: CK, Creatine Phosphokinase
CPT Code: 82550
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red top tube, or green-top (heparin) tube.
Collection: Separate serum or plasma from cells. Avoid prolonged contact of serum or plasma with red cells.
Storage and Stability: Maintain specimen at room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Use: Test for acute myocardial infarct and for skeletal muscular damage; elevated in some patients with myxedema (hypothyroidism), malignant hyperthermia syndrome, and muscular dystrophy. CK is a marker for Duchenne muscular dystrophy, with elevations of 20 to 200 times normal.

References Ranges:

  • Male: 24-204 units/L
  • Female: 24- 173 units/L
Special Request: State patient's sex on the requisition form.

Test Code: RL80
Synonyms: C-Reactive Protein
CPT Code: 86140
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.
Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.
References Ranges: 2 mL

Use: CRP is an acute phase reactant, which can be used as a test for inflammatory diseases, infections, and neoplastic diseases. Progressive increases correlate with increases of inflammation/injury. CRP may be used to detect early postoperative wound infection and to follow therapeutic response to anti-inflammatory agents.
Test Code: 1038
Synonyms: Cardiac C-Reactive Protein (CRP), CRP High Sensitivity, cardiac risk assessment
CPT Code: 86141
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube.
Collection: Separate serum or plasma from cells within one hour of collection.
Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.
Use: This test can be used to help evaluate a person's risk of cardiovascular and peripheral vascular disease.
Test Code: 1167
CPT Code: 82610
Specimen: Serum or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or green-top (heparin) tube.
Collection: Separate serum or plasma from red blood cells.
Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Use: Cystatin C may be used to as an alternative test to creatinine to screen and monitor kidney function. Serum concentrations of cystatin C are almost totally dependent on glomerular filtration rate (GFR). A reduction in GFR causes a rise in the concentration of cystatin C.

Special Request: Overnight fasting is preferred.
Test Code: 1051
CPT Code: 85379
Specimen: Plasma, Frozen
Volume: 2 mL
Container: Blue-top (sodium citrate) tube

Collection: Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes MUST BE filled to completion to ensure a proper blood to anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood. A discard tube is not required prior to collection of coagulation samples. When non-citrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Plasma samples are stable for eight hours at room temperature. If the sample cannot make it to the laboratory for testing within eight hours, the specimen should be frozen immediately and maintained frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage and Stability: Freeze

Use: D-dimer tests are used to help rule out the presence of an inappropriate blood clot (thrombus). Some of the conditions that the D-dimer test is used to help rule out include:

  • Deep vein thrombosis (DVT), pulmonary embolism (PE), Stroke
  • This test may be used to determine if further testing is necessary to help diagnose diseases and conditions that cause hypercoagulability, a tendency to clot inappropriately.
  • A D-dimer level may be used to help diagnose disseminated intravascular coagulation (DIC) and to monitor the effectiveness of DIC treatment.
Test Code: RL96
Synonyms: DHEA-SO4; Dehydroepiandrosterone Sulfate
CPT Code: 82627
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If a red top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Stable for 14 day at room temperature/refrigerated/frozen.

Use: The test is usually ordered along with other male hormones to evaluate adrenal gland function, distinguish DHEA-S-secreting conditions caused by adrenal gland from other originals.

The test is also used to help diagnose women with infertility, amenorrhea, or hirsutism to identify the source of excessive androgen.

The test helps in the evaluation of androgen excess (hirsutism and/or virilization), including Stein-Leventhal syndrome and adrenocortical diseases, including congenital adrenal hyperplasia and adrenal tumor.

The test may be ordered along with other hormone tests to help diagnose the cause of development of masculine physical characteristics (virilization) in young girls and early (precocious) puberty in young boys.

Test Code: 1052
Synonyms: Lanoxin®
CPT Code: 80162
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. Blood specimen must be drawn six to eight hours after the administration of the last dose (levels drawn earlier than six hours after a dose will be artificially elevated). Collect specimen just before dose if steady-state estimate is needed. The steady-state is usually attained in five days.

Storage and Stability: Refrigerate. Specimen stable for 14 day under room temperature/refrigerated/frozen.
Special Instructions: Be sure patient is not on digitoxin.
Use: To diagnose and prevent digoxin toxicity; prevent underdosage; monitor therapeutic drug level; prevention and therapy of cardiac arrhythmias.
Test Code: RL40
CPT Code: 82248
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or green-top (lithium heparin) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Specimen stable for 2 days at room temperature, 3 day under refrigerated and 14 days under frozen.

Use: The test is used to evaluate liver and biliary disease. Increased direct bilirubin occurs with biliary diseases, including both intrahepatic and extrahepatic lesions. Hepatocellular causes of elevation include hepatitis, cirrhosis, and advanced neoplastic states. Increased with cholestatic drug reactions, Dubin-Johnson syndrome, and Rotor syndrome.
Test Code: 1054
CPT Code: 82668
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is used to help diagnose and differentiate different types of anemias. It is also used to determine the amount of erythropoietin produced for the level of anemia.

The test is also ordered to evaluate the kidney's ability to produce sufficient erythropoietin for people with chronic kidney disease.

The test may be also ordered to help diagnose polycythemia.
Test Code: RL99
Synonyms: E2
CPT Code: 82670
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.
Use: This estradiol assay is designed for the investigation of fertility of women of reproductive age and for the support of in vitro fertilization.
Test Code: RL76
Synonyms: E3, Unconjugated Estriol, Pregnancy Estriol
CPT Code: 82677
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube

Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. All specimens should be drawn at the same time of day to allow comparison of values.

Storage and Stability: Refrigerated. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is ordered to evaluate fetal distress and placental function in the management of patients facing complications such as preëclampsia, fetal growth retardation, diabetes, Rh immunization, choriocarcinoma, and hydatidiform mole. May be elevated in hydrops fetalis in the presence of a dying fetus. May be low in the presence of a living anencephalic fetus.
Test Code: RL81
Synonyms: E1
CPT Code: 82679
Specimen: Serum of plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or lavender-top (EDTA) tube.
Collection: If a red-top tube or lavender-top tube is used, transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Refrigerate.
Special request: No isotopes administered 24 hours prior to venipuncture.

Use: The test is used to evaluate postmenopausal vaginal bleeding due to peripheral conversion of androgenic steroids. Increased estrone levels may be associated with increased levels of circulating androgens and their subsequent peripheral conversion.
Test Code: 1055
Synonyms: Zarontin®
CPT Code: 80168
Specimen: Serum of plasma
Volume: 2 mL
Container: Red-top tube, lavender-top (EDTA) tube or green-top (heparin) tube. Do not use a gel-barrier tube.

Collection: Transfer separated serum or plasma to a plastic transport tube. Oral: peak: two to four hours after dose; trough: immediately prior to next dose. Peak or trough levels may be used to monitor therapy because blood levels are fairly constant.

Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.
Use: Diagnose and prevent ethosuximide toxicity; prevent underdosage; monitor therapeutic drug level.
Test Code: 1080
Synonyms: Blood Alcohol Level
CPT Code: 80320
Specimen: Whole blood or serum
Volume: 7 mL
Container: Gray-top (sodium fluoride) tube (preferred), Red-top tube, gel-barrier tube, green-top (heparin) tube. Submit original unopened tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Stable for 14 days at room temperature/refrigerated/frozen.

Use: Used to diagnose alcohol intoxication and determine appropriate therapy; detect alcoholism and to monitor ethanol treatment for methanol intoxication. Clinical Diagnostic purpose only.

Special Instructions: This is test is for clinical diagnosis purpose only.
Test Code: 1057
CPT Code: 82728
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerated. Specimen stable at room temperature for 3 days, 5 days under refrigerated and 14 days under frozen.

Use: The ferritin test is to check a person's iron storage capability in body. The test may be ordered along with other iron test to diagnose hypochromic, microcytic anemias.
Test Code: RB09
Synonyms: Folic acid
CPT Code: 82746
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.
Collection: If a red-top tube is used, transfer separated serum immediately to a plastic transport tube. Avoid hemolysis.
Storage and Stability: Refrigerate

Use: Detect folate deficiency; monitor therapy with folate; evaluate megaloblastic and macrocytic anemia; evaluate alcoholic patients and those with prior jejunoileal bypass for morbid obesity or those with intestinal blind-loop syndrome.
Test Code: RL88
Synonyms: Triiodothyronine (T3), Free
CPT Code: 84481
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.
Use: The test is used to evaluate thyroid function and assess abnormal binding protein disorders.
Test Code: RL24
Synonyms: Free Thyroxine, T4 Free Direct
CPT Code: 84439
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is used to evaluate thyroid function and assess abnormal binding protein disorders. Free T4 may be indicated when binding globulin (TBG) problems are perceived, or when conventional test results seem inconsistent with clinical observations. It is normal in subjects with high thyroxine-binding globulin hormone binding who are euthyroid (i.e., free thyroxine should be normal in nonthyroidal diseases). It should be normal in familial dysalbuminemic hyperthyroxinemia.
Test Code: RL95
CPT Code: 84402, 84403
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The percentage is calculated based on the ratio of free testosterone and the total testosterone. The test is ordered to evaluate hirsutism and masculinization in women; evaluate testicular function in clinical states where the testosterone binding proteins may be altered (obesity, cirrhosis, thyroid disorders).
Test Code: RL94
Synonyms: Free testosterone direct, Free testosterone (direct) serum
CPT Code: 84402
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is ordered to evaluate hirsutism and masculinization in women; evaluate testicular function in clinical states where the testosterone binding proteins may be altered (obesity, cirrhosis, thyroid disorders).

Special Request: State patient's age and sex.
Test Code: RL83
Synonyms: Follicle-stimulating Hormone, Pituitary Gonadotropin
CPT Code: 83001
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. Avoid hemolysis.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test can be ordered along with other hormone tests to help determine and diagnose the cause of infertility, conditions associated with dysfunction of the ovaries or testicles. Excessive FSH and LH are found in hypogonadism, anorchia, gonadal failure,1 complete testicular feminization syndrome, menopause, Klinefelter syndrome, alcoholism, and castration. FSH and LH are pituitary products, useful to distinguish primary gonadal failure from secondary (hypothalamic/pituitary) causes of gonadal failure, menstrual disturbances, and amenorrhea. Useful in defining menstrual cycle phases in infertility evaluation of women and testicular dysfunction in men. FSH is commonly used with LH, which also is a gonadotropin. Both are low in pituitary or hypothalamic failure. FSH and LH levels are high following menopause.
Test Code: 1098
CPT Code: 82777
Specimen: Serum or plasma
Volume: 2 mL
Container: Gel-barrier tube (preferred), red-top tube, or lavender-top tube.
Collection: Transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Refrigerate

Use: The gamma-glutamyl transferase (GGT) test may be used to determine the cause of elevated alkaline phosphatase (ALP). Both ALP and GGT are elevated in disease of the bile ducts and in some liver diseases, but only ALP will be elevated in bone disease. Therefore, if the GGT level is normal in a person with a high ALP, the cause of the elevated ALP is most likely bone disease.
Test Code: 1059 (peak), 1060 (trough)
CPT Code: 80170 (x2)
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, or green-top (heparin) tube. DO NOT use a gel-barrier tube.

Collection: Transfer separated serum or plasma to a plastic transport tube. Both peak and trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose. Peak samples should be drawn 45 to 60 minutes after an IM injection, 30 minutes after the end of a 30-minute IV infusion, or immediately after a 60-minute IV infusion.

Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: Gentamicin is primarily used to treat serious infections caused by aerobic gram-negative bacilli. The test is used to diagnose and prevent gentamicin toxicity; prevent underdosage; monitor therapeutic drug level.
Test Code: RL42
Synonyms: Gamma-Glutamyl Transferase, γ-Glutamyl Transferase, Glutamyl Transpeptidase
CPT Code: 82977
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube, red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The gamma-glutamyl transferase (GGT) test may be used to determine the cause of elevated alkaline phosphatase (ALP). Both ALP and GGT are elevated in disease of the bile ducts and in some liver diseases, but only ALP will be elevated in bone disease. Therefore, if the GGT level is normal in a person with a high ALP, the cause of the elevated ALP is most likely bone disease.
Test Code: RL01
CPT Code: 82947
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube (preferred) or red-top tube.
Collection: Separate serum from cells within 45 minutes of collection. Label specimen as serum.
Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is used to detect high blood glucose (hyperglucemia) and low blood glucose (hypoglycemia). The test is also used to diagnose diabetes mellitus; evaluate disorders of carbohydrate metabolism including alcoholism; evaluate acidosis and ketoacidosis; evaluate dehydration, coma, hypoglycemia of insulinoma, neuroglycopenia. The test is also used to monitor glucose levels in people diagnosed with diabetes.

Special Request: Patient should be fast for 12 hours.
Test Code: 1082 (1 Hr), 1084 (2 Hr), 1083 (3 Hr)
CPT Code: 82947, 82950, 82951
Specimen: Serum or plasma
Volume: 2 mL serum of plasma each tube.
Container: Gel-barrier tube (4) or grey-top (sodium fluoride/potassium oxalate plasma) tube (4)

Collection: Submit 1 mL serum or plasma for fasting and one-hour, two-hour and three-hour specimens. Separate serum or plasma from cells within 45 minutes of venipuncture. Gray-top tubes only, may be submitted without centrifugation. Label each tube with the patient's name and collection time interval (i.e., fasting, and two-hour)

Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: The test is used to detect high blood glucose (hyperglucemia) and low blood glucose (hypoglycemia). The test is also used to diagnose diabetes mellitus; evaluate disorders of carbohydrate metabolism including alcoholism; evaluate acidosis and ketoacidosis; evaluate dehydration, coma, hypoglycemia of insulinoma, neuroglycopenia. The test is also used to monitor glucose levels in people diagnosed with diabetes.

The OGTT is used to work up glycosuria with- out hyperglycemia (e.g., to work up renal glycosuria). It is used to predict perinatal morbidity in pregnancy, to diagnose gestational diabetes. Risks of fetal abnormality and perinatal mortality are increased with abnormal carbohydrate metabolism in pregnancy.

Special Request: Patient should be active and eat a regular diet that includes at least 150 grams of carbohydrate daily for three days prior to the test. Patient should be instructed not to eat or drink anything except water for at least eight hours and not more than 14 hours before the test. Patients should also be advised to discontinue, whenever possible, all nonessential medication that can affect glucose metabolism at least three days before testing.
Test Code: 1124
Synonyms: Human Growth Hormone (hGH), Somatotropic Hormone (STH)
CPT Code: 83003
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection. Label tube with time of collection and patient's name.
Storage and Stability: Refrigerate

Use: Pituitary function test useful in the diagnosis of hypothalamic disorder, hypopituitarism, acromegaly, and ectopic growth hormone production by neoplasm.
Test Code: 1062
CPT Code: 83010
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells.
Storage and Stability: Room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.

Use: Haptoglobin binds to hemoglobin, and carries it to the reticuloendothelial system. Thus, haptoglobin is useful in work-up for hemolytic states. The test is primarily used to help detect and evaluate hemolytic anemia and to distinguish it from anemia due to other causes, but not able to diagnose the cause of hemolysis.

Special Request: Avoid exercise prior to collection and hemolysis from traumatic venipuncture.
Test Code: RL82
Synonyms: Hemoglobin A1C
CPT Code: 83036
Specimen: Whole blood
Volume: 4 mL (pediatric EDTA whole blood tubes may be used. Please place the entire collection in a transport tube for shipment to laboratory).
Container: Lavender-top (EDTA) tube, green-top (lithium heparin) tube, or gray-top (sodium fluoride) tube.

Collection: The usual precautions in the collection of venipuncture samples should be observed. The sample must be free of clots. Samples with any hematocrit disorders can lead to erroneous results. Send the entire tube to the laboratory.

Storage and Stability: Maintain specimen at room temperature. Specimen stable for 14 days at room temperature/refrigerated/frozen.
Use: The test may be used to screen and diagnose diabetes and prediabetes in adults.
Test Code: RL21
Synonyms: High-density Lipoprotein Cholesterol (HDL-C); Alpha-Lipoprotein Cholesterol; HDL Cholesterol; HDLC
CPT Code: 83718
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube, transport tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate

Use: The test for high-density lipoprotein cholesterol (HDL-C) is used along with other lipid tests to screen for unhealthy levels of lipids and to determine the risk of developing heart disease.
Test Code: 1148
Synonyms: Human Leukocyte Antigen B27
CPT Code: 81374
Specimen: Whole blood
Volume: Fill completely
Container: Lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain at room temperature

Use: Evaluate spondyloarthritis and other disorders associated with HLA-B27. The HLA-B27 test is primarily ordered to help strengthen or confirm a suspected diagnosis of ankylosing spondylitis (AS), reactive arthritis, juvenile rheumatoid arthritis (JRA), or sometimes anterior uveitis.
Test Code: B071
Synonyms: Homocystine
CPT Code: 83090
Specimen: Plasma (preferred) or Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: Homocysteine may be ordered as part of a screen for people at high risk for heart attack or stroke. Tests for both a urine and blood homocysteine may be used to help diagnose homocystinuria if a health practitioner suspects that an infant or child may have this inherited disorder. A health practitioner may order a homocysteine test to determine if a person has a vitamin B12 or folate deficiency. The homocysteine concentration may be elevated before B12 and folate tests are abnormal.
Test Code: 1063
Synonyms: Immunoglobulin A
CPT Code: 82784
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Storage and Stability: Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.

Use: Evaluate humoral immunity; monitor therapy in IgA myeloma.
Test Code: 1118
Synonyms: IgE
CPT Code: 82785
Specimen: Serum
Volume: 0.8 mL (0.3 mL minimum)
Container: Red-top tube or gel-barrier tube

Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Room temperature - 2 days; Refrigerated - 7 days; Frozen - 14 days; Freeze/thaw cycles - 3x maximum

Test Code: 1157
Synonyms: Insulin-like Growth Factor 1; SM-C/IGF-1; Somatomedin-C, Sulfation Factor
CPT Code: 84305
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: Separate serum from cells. Transfer separated serum to a plastic transport tube. Please include the patient’s age on the test request form.
Storage and Stability: Refrigerate, 7 days

Use: Results of the insulin-like growth factor-1 assay are to be used in conjunction with other clinical and laboratory data to assist the clinician in the assessment of growth disorders.
Test Code: 1064
Synonyms: Immunoglobulin G, Quantitative
CPT Code: 82784
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Storage and Stability: Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.

Use: Evaluate humoral immunity; monitor therapy in IgG myeloma; evaluate patients, especially children and those with lymphoma, with propensity to infections.
Test Code: 1065
Synonyms: Immunoglobulin M, Quantitative
CPT Code: 82784
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: Spin down and transfer to a plastic tube within 30-45 minutes

Storage and Stability: Samples suspected of having macroglobulins or cryoglobulins should be drawn and held at 37°C. Samples suspected of containing cold agglutinins should not be refrigerated prior to serum separation from clot.

Use: Evaluate humoral immunity; establish the diagnosis and monitor therapy in macroglobulinemia of Waldenström or plasma cell myeloma. IgM levels are used to evaluate likelihood of in utero infections or acuteness of infection.
Test Code: 1066
CPT Code: 86336
Specimen: Serum, frozen
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Collection: Transfer the serum frozen in purple tube with screw cap. Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage and Stability: Freeze
Use: Assess the function of the antral follicles the dominant follicle/corpus luteum of the ovaries in women.
Test Code: 1125
Synonyms: Immunoreactive Insulin
CPT Code: 83525
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: Separate serum or plasma from cells within 45 minutes of collection. Patient should be fasting at time of collection.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: Insulin testing has several possible uses. Insulin testing may be used to help:

• Diagnose an insulinoma
• Diagnose the cause of hypoglycemia in an individual with signs and symptoms
• Identify insulin resistance
• Monitor the amount of insulin produced by the beta cells in the pancreas (endogenous); in this case, a C-peptide test may also be done
• Determine when a type 2 diabetic might need to start taking insulin to supplement oral medications
• Determine and monitor the success of an islet cell transplant intended to restore the ability to make insulin, by measuring the insulin-producing capacity of the transplant
Test Code: 1067
Synonyms: PTH Whole Molecule; Parathyroid Hormone
CPT Code: 83970
Specimen: Plasma (preferred)
Volume: 2 mL
Container: Lavender-top (EDTA) tube (preferable)
Collection: Transfer separated plasma into a plastic transport tube clearly labeled as "EDTA Plasma" and maintain at refrigerated temperature.
Storage and Stability: Refrigerate, stable for 3 days
Use: Diagnosis of parathyroid disease and other diseases of calcium homeostasis; monitoring patients undergoing renal dialysis.
Test Code: 1068
Synonyms: Intrinsic Factor Blocking Antibody (Ab), Anti-intrinsic Factor
CPT Code: 86340
Specimen: Serum
Volume: 2 mL
Container: Gel-barrier tube, or red-top tube
Collection: If red-top tube is used, transfer separated serum from cells into a plastic transport tube within 45 minutes of collection
Storage and Stability: Ambient, Refrigerate, Frozen Stable for 14 days.

Use: • To help determine the cause of a vitamin B12 deficiency
• To confirm a diagnosis of pernicious anemia.
Test Code: RL74
Synonyms: Serum Iron; Serum Fe
CPT Code: 83540
Specimen: Serum (preferred) or plasma (lithium heparin only). EDTA plasma causes decreased results.
Volume: 2 mL
Container: Gel-barrier tube, transport tube, or green-top (heparin) tube; do not use EDTA or oxalate anticoagulants.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain at room temperature
Use: Aid in the evaluation of a number of conditions involving red cell production and destruction, iron metabolism, or iron transport.
Test Code: 1010

Synonyms: Fe and TIBC, TIBC and Iron, Total Iron-binding Capacity (TIBC), Transferrin Saturation, Unsaturated Iron-binding Capacity (UIBC), Iron and Total Iron-binding Capacity (TIBC)

CPT Code: 83540; 83550
Specimen: Serum (preferred) or plasma (lithium heparin only). EDTA plasma causes decreased results.
Volume: 2 mL
Container: Gel-barrier tube, transport tube, or green-top (heparin) tube; do not use EDTA or oxalate anticoagulants.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate

Use: Differential diagnosis of anemia, especially with hypochromia and/or low MCV. The percent saturation sometimes is more helpful than is the iron result for iron deficiency anemia.
Test Code: 0343
Synonyms: Kynurenate
CPT Code: 83520
Specimen: Urine
Volume: 5 mL
Container: Plastic urine container
Storage and Stability: Room temperature
Use: This test is used to check Vitamin B2 deficiency
Test Code: RL54
Synonyms: LDH; Lactic Acid Dehydrogenase Isoenzymes; LD Isoenzymes; LDH Isoenzymes
CPT Code: 83615
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: Separate serum from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature. Do not freeze. Do not refrigerate for more than three days.

Room Temperature: 7 Days
Refrigerated: 3 Days
Frozen: Unstable
Freeze/Thaw cycles: Unstable

Use:

The LD test can be used as a general marker of injury to cells. Elevated serum levels of LDH have been observed in a variety of disease states. The highest levels are seen in patients with megaloblastic anemia, disseminated carcinoma, and shock.
Test Code: 1069
Synonyms: Lactic Acid Dehydrogenase (LD)
CPT Code: 83605
Specimen: Plasma
Volume: 2 mL
Container: Gray-top (sodium fluoride/potassium oxalate or sodium fluoride/sodium heparin) tube

Collection: Keep gray-top tube on ice. Draw blood in gray-top tube. Mix well by gentle inversion at least six times. Return to ice bath to cool. Avoid hand-clenching and, if possible, avoid use of a tourniquet. A tourniquet with patient clenching and unclenching hand will lead to high potassium and lactic acid buildup from the hand muscles, and pH will decrease. It is best to avoid a tourniquet for electrolytes and lactic acid or to release it after blood begins to flow into the tube. If the tourniquet is released before blood is drawn, wait about a minute before drawing. Within 15 minutes of draw, separate the plasma from blood by centrifugation for 10 minutes. Immediately transfer the plasma portion of the sample to a labeled plastic transport tube. Avoid excessive forces that contribute to hemolysis.

Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 7 Days
Frozen: 14 Days
Freeze/Thaw cycles: Stable x3

Use:

The lactate test is primarily ordered to help determine if someone has lactic acidosis, a level of lactate that is high enough to disrupt a person's acid-base (pH) balance.
Test Code: RL22
Synonyms: Low-Density Lipoprotein Cholesterol; LDL; LDL-C, Direct; Direct LDL; Direct LDLC; LDLC, Direct
CPT Code: 83721
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw cycles: Stable x3

Use:

The test for low-density lipoprotein cholesterol (LDL-C) is used as part of a lipid profile to predict an individual's risk of developing heart disease.
Test Code: RL84
Synonyms: Luteinizing Hormone; Interstitial Cell-stimulation Hormone
CPT Code: 83002
Specimen: Serum
Volume: 2 mL
Container: Red top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw cycles: Stable x3

Use:

In both women and men, LH is often used in conjunction with other tests (FSH, testosterone, estradiol and progesterone):

• In the workup of infertility
• To aid in the diagnosis of pituitary disorders that can affect LH production
• To help diagnose conditions associated with dysfunction of the ovaries or testicles
Test Code: 1070

Synonyms: Akten™, AneCream™, Anestafoam™, Band-Aid® Hurt-Free™, Burn Jel®, L-M-X® 4, L-M-X® 5, LidaMantle®, Lidoderm®, LTA® 360, Premjact®, Regenecare®, Solarcaine® Cool Aloe Burn Relief, Topicaine®, Unburn®, Xylocaine®

CPT Code: 80176
Specimen: Serum or plasma
Volume: 2 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Draw specimens 12 hours after initiating therapy for arrhythmia prophylaxis, then every 24 hours thereafter. Obtain specimens every 12 hours when cardiac or hepatic insufficiency exists.

Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw cycles: Stable x3

Use: Lidocaine may control ventricular arrhythmias caused by digitalis toxicity and those that develop during cardiac surgery, cardiac catheterization, or cardioversion.
Test Code: 1071
CPT Code: 83690
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, or green-top (heparin) tube.
Collection: Separate serum within 45 minutes of collection
Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw cycles: Stable x3

Use: The blood test for lipase is most often used, along with an amylase test, to help diagnose and monitor acute pancreatitis.
Test Code: 1168
Synonyms: Lp “Little a”
CPT Code: 83695
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, green-top (heparin) tube, or blue-top (citrate) tube.
Collection: Separate serum or plasma from cells as soon as possible (within two hours).
Storage and Stability: Refrigerate. Stable refrigerated for 14 days or frozen (if greater than 14 days)

Use: To evaluate disorders of lipid metabolism and to assess coronary heart disease in specific populations. The Lp(a) test is used to identify an elevated level of lipoprotein (a) as a possible risk factor in the development of cardiovascular disease (CVD). The test may be used in conjunction with a routine lipid profile to provide additional information about a person's risk for CVD.
Test Code: 1072
Synonyms: Lithobid
CPT Code: 80178
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate, Stable for 14 days.

Use: The test is used to measure the blood lithium level to provide the health care providers whether the lithium concentration is in the therapeutic range. It can also be used to monitor blood lithium level for patients with lithium treatment. Lithium tests may also be ordered if toxicity is suspected.
Test Code: 1073
Synonyms: Lysergic Acid Diethylamide
CPT Code: 80302
Specimen: Serum or plasma, protected from light
Volume: 7 mL
Container: Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Collection: Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube. Wrap specimen in foil to protect from light.

Storage and Stability: Freeze. Protect from light.

Room Temperature: Unnaceptable
Refrigerated: 2 Weeks
Frozen: 6 Months

Use: Detect presence of lysergic acid diethylamide (LSD), an illicit hallucinogen
Test Code: 1166
Synonyms: Lipoprotein-associated Phospholipase A2, PLAC, Platelet-activating Factor Acetylhydrolase, PAF-AH
CPT Code: 83698
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube.
Collection: Transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Refrigerate

Use: Used in conjunction with clinical evaluation and patient risk assessment as an aid in predicting risk for coronary heart disease and ischemic stroke associated with atherosclerosis. The Lp-PLA2 test is sometimes used to help evaluate a person's risk of developing coronary heart disease (CHD) or to help determine the risk of having an ischemic stroke.
Test Code: 1074
Synonyms: Mg
CPT Code: 83735
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red top tube, gel barrier tube, or green-top (lithium heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Maintain specimen at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: A magnesium test is used to measure the level of magnesium in the blood (or sometimes urine). Magnesium levels may be checked as part of an evaluation of the severity of kidney problems and/or of uncontrolled diabetes and may help in the diagnosis of gastrointestinal disorders. Magnesium testing may be ordered as a follow up to chronically low blood levels of calcium and potassium. It also may be ordered when a person has symptoms that may be due to a magnesium deficiency, such as muscle weakness, twitching, cramping, confusion, cardiac arrhythmias, and seizures.
Test Code: 6037
CPT Code: 83735
Specimen: Red blood cells (RBCs)
Volume: 2 mL
Container: Green-top (heparin) tube, lavender-top (EDTA) tube, royal blue-top (EDTA) tube, or tan-top lead-free tube

Collection: Centrifuge tube within 45 minutes of collection and separate plasma from cells. Discard the plasma. Using the original collection tube, submit only the RBCs to the laboratory.

Storage and Stability: Maintain specimen at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: To evaluate magnesium deficiency.
Test Code: 0336
Synonyms: MMA
CPT Code: 83921
Specimen: Urine
Volume: 10 mL
Container: Plastic urine container, no preservative

Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.

Storage and Stability: Ambient temperature, Refrigerated

Use: Vitamin B12 deficiency
Test Code: 1078
Synonyms: Albumin, Random Urine
CPT Code: 82043
Specimen: Urine (random)
Volume: 5 mL
Container: Plastic urine container
Collection: Collect random or 24 hour urine without preservatives. pH must be 4 to 8.
Storage and Stability: Maintain specimen at room temperature

Room Temperature: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: This test is useful in the management of patients with relatively early diabetes mellitus to assist in avoiding or delaying the onset of diabetic renal disease.
Test Code: RQ13
Synonyms: Albumin/Creatinine Ratio, Random Urine, UARC
CPT Code: 82043; 82570
Specimen: Urine (random)
Volume: 5 mL
Container: Sterile plastic container, no preservative
Collection: Collect random urine without preservatives. pH must be 4 to 8.
Storage and Stability: Maintain specimen at room temperature

Room Temperature: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: This test is useful in the management of patients with relatively early diabetes mellitus to assist in avoiding or delaying the onset of diabetic renal disease.
Test Code: 1079
CPT Code: 83874
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: To diagnose skeletal or myocardial muscle injury.
Test Code: 1101
Synonyms: Acecainide1, Procainamide, NAPA
CPT Code: 80192
Specimen: Serum or plasma
Volume: 2 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Oral treatment: peak: 75 minutes after dose; trough: immediately before next dose. I.V. treatment: immediately after loading dose; 2, 6, 12, and 24 hours after starting I.V. maintenance.

Storage and Stability: Refrigerate

Room Temperature: 2 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: N-Acetylprocainamide is the metabolite of the prodrug procainamide, a drug used in a variety of arrhythmias. The half-life of procainamide is two to six hours and for NAPA is eight hours.
Test Code: 1103
Synonyms: Bone-specific Alkaline Phosphatase (BAP), Skeletal Alkaline Phosphatase
CPT Code: 84080
Specimen: Serum
Volume: 2 mL

Container: Gel-barrier tube or transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Collection: If red-top tube is used, transfer separated serum from cells into a plastic transport tube within 45 minutes of collection. Please submit separate frozen specimens for each test requested.

Storage and Stability: Store sample at 2°C to 8°C if testing will be performed within 24 to 48 hours. Specimens held longer should be frozen at -20°C to -70°C.

Use: To aid in the diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover
Test Code: RB02
Synonyms: Activated Partial Thromboplastin Time, aPTT, APTT
CPT Code: 85730
Specimen: Serum (preferred) or plasma
Volume: Fill Completely
Container: Light-blue top (3.2% sodium citrate)

Collection and Storage: Specimens are stable at room temperature for 24 hours. If testing cannot be completed within 24 hours, specimens should be centrifuged for at least 10 minutes at 1500xg. Plasma should then be frozen until tested. Freeze immediately and maintain frozen until tested.

Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood.

Use: The PTT is used primarily to investigate unexplained bleeding or clotting. It may be ordered along with a prothrombin time (PT) test to evaluate hemostasis, the process that the body uses to form blood clots to help stop bleeding. These tests are usually the starting points for investigating excessive bleeding or clotting disorders.
Test Code: 1108
Synonyms: Dilantin-125®, Dilantin®, Free and Total Phenytoin, Phenytek®
CPT Code: 80185
Specimen: Serum or plasma
Volume: 2 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Collect specimen just prior to next dose. Serum or plasma must be separated from cells within 45 minutes of collection. Send serum or plasma in a plastic transport tube.

Storage and Stability: Maintain specimen at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate toxicity; monitor therapeutic levels of the drug Phenytoin.
Test Code: RL39
Synonyms: Inorganic Phosphate
CPT Code: 84100
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.

Storage and Stability: Maintain specimen at room temperature

Room Temperature: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Phosphorus tests are most often ordered along with other tests to help diagnose and/or monitor treatment of various conditions that cause calcium and phosphorus imbalances.
Test Code: RL06
CPT Code: 84132
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, or green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection; avoid hemolysis.
Storage and Stability: Maintain at room temperature or refrigerate

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate electrolyte balance for a routine physical. A potassium test is used to detect abnormal concentrations of potassium, including high potassium (hyperkalemia) and low potassium (hypokalemia).
Test Code: 1109
Synonyms: Transthyretin
CPT Code: 84134
Specimen: Serum
Volume: 2 mL (adult) 1 mL (pediatric)
Container: Red-top tube or gel-barrier tube
Storage and Stability: Maintain at room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate protein malnutrition, total parenteral nutrition, and liver dysfunction.
Test Code: 1099
Synonyms: NT-proBNP, Propeptide of Brain Natriuretic Peptide, B-type Natriuretic Peptide, N-terminal pro b-type Natriuretic Peptide
CPT Code: 83880
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If ared-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate

Room Temperature: 3 Days
Refrigerated: 3
Frozen: 12 Months
Use: Primarily used to help detect, diagnose, and evaluate the severity of heart failure. Several BNP or NT-proBNP tests may be done over a period of time when an individual is being treated for heart failure to monitor the effects of therapy. Support a diagnosis of congestive heart failure (CHF).
Test Code: RL67
CPT Code: 84144
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Room Temperature

Room Temperature: 15 Days
Refrigerated: 15 Days
Frozen: 15 Days
Freeze/Thaw Cycles: Stable x3

Use: Progesterone levels are measured:
  • During an infertility assessment, when a woman is having trouble getting pregnant and her health care provider wants to verify that she is ovulating normally; the test may be ordered a few times during a woman's menstrual cycle to evaluate the change in progesterone concentrations
  • When it is necessary to determine when ovulation has occurred and following drug therapy to induce ovulation
  • When symptoms, such as abdominal pain and spotting, suggest an ectopic pregnancy or threatened miscarriage
  • On a regular basis when a woman requires progesterone replacement therapy to help maintain her pregnancy
  • Periodically throughout a high-risk pregnancy to monitor placenta and fetal health
  • When a non-pregnant woman is experiencing abnormal uterine bleeding
Test Code: RL85
Synonyms: PRL
CPT Code: 84146
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Refrigerate

Room Temperature: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Prolactin levels may be used for several reasons. Prolactin is a hormone produced by the pituitary gland and its primary role is to help initiate and maintain breast milk production in pregnant and nursing women. A test can be used to determine the cause for galactorrhea (inappropriate lactation). Pituitary function test is also useful in the detection of prolactin-secreting pituitary tumors (microadenomas, macroadenomas) with or without galactorrhea, with or without structural evidence of sellar enlargement.
Test Code: RL44
Synonyms: Prostate Specific Antigen
CPT Code: 84153
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Maintain at room temperature

Use: Prostate-specific antigen (PSA) is a glycoprotein produced by the epithelial cells lining the prostatic ducts and acini. Normally, it is secreted into the prostatic ducts and is present only in prostate tissue, prostatic fluid, and seminal plasma. PSA is produced by normal, hyperplastic, and cancerous prostatic tissue. PSA is used as a tumor marker for the early detection of prostate cancer and in other areas of prostate disease management. The Prostate-Specific Antigen Best Practice Statement: 2009 Update published by the American Urologic Association describes the use of PSA testing for:

  • The evaluation of men at risk for prostate cancer
  • Assistance in pretreatment staging
  • Risk assessment posttreatment monitoring
  • Use as a guide in management of men who recur after primary or secondary therapy
Test Code: 0340
Synonyms: Pyroglutamate
CPT Code: 83921
Specimen: Urine
Container: Plastic urine container, no preservative
Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.
Storage and Stability: Ambient temperature, Refrigerated
Use: Elevated level of pyroglutamic acid is an indication of glutathione status.
Test Code: 0339
Synonyms: 2,3-PYRIDINEDICARBOXYLIC ACID; Pyridine-2,3-dicarboxylic acid; NSC 13127
CPT Code: 83921
Specimen: Urine
Volume: 5 mL
Container: Plastic urine container, no preservative

Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.

Storage and Stability: Ambient temperature, Refrigerated
Use: Quinolinic acid is a neurotoxic metabolite of the kynurenine pathway that accumulates within the central nervous system following immune activation. It can occur in neurodegenerative disorders, such as Parkinson's disease, Huntington's and Alzheimer's disease, in stroke, in epilepsy, in multiple sclerosis, in amyotrophic lateral sclerosis, and in mental failures, such as schizophrenia and depression.1

References: 1. http://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+7511
Test Code: RH09
Synonyms: T3, Reverse
CPT Code: 84482
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Collection: Separate serum from cells within 45 minutes of collection. If a tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.

Storage and Stability: Refrigerate. Stable for 14 days.
Use: An aid in the diagnosis of the "sick euthyroid" syndrome
Test Code: 6033
Synonyms: Rh Type, Rh(D) Typing
CPT Code: 86901
Specimen: Whole Blood
Volume: 2 mL
Container: Lavender-top (EDTA) tube (preferred), pink-top (K2EDTA) tube, or plain red-top tube.

Collection: Specimens should be tested as soon as possible or within 72 hours of collection. Samples that cannot be tested immediately should be stored at 2°C to 8°C. DO NOT FREEZE

Storage and Stability: Ambient temperature (3 days), Refrigerated (7 days), Frozen (unacceptable)

Use: This test is used to help determine Rh type for transfusion candidates and Rh immune globulin candidacy for prenatal and postpartum patients. Rh typing of expectant mothers may indicate potential for Rh hemolytic disease of the fetus/newborn.
Test Code: RL48
Synonyms: RF Titer, Rheumatoid Factor (RF)
CPT Code: 86431
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Stable for 14 days.
Use: Help in the differential diagnosis and prognosis of arthritic disorders
Test Code: 1158
Synonyms: Antiextractable Nuclear Antigen, Anti-RNP
CPT Code: 86235
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Detect antibodies associated with SLE and mixed connective tissue disease. Anti-RNP is found with a variety of rheumatoid diseases with high titers associated mainly with MCTD.
Test Code: 1114
CPT Code: 80299
Specimen: Serum or plasma
Volume: 3 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Optimal sampling time after dosage is two to six hours. Optimal resampling time after change in dosage is six hours.

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: This test is used to detect a high level of salicylate in the blood. It may be used to help diagnose an overdose (salicylate poisoning) or to monitor a person who takes a prescription-strength salicylate.
Test Code: RL33
Synonyms: Erythrocyte Sedimentation Rate
CPT Code: 85652
Specimen: Whole Blood
Volume: 2 mL
Container: Lavender-top (EDTA) tube
Collection: Invert tube immediately 8-10 times once tube is filled at time of collection
Storage and Stability: Refrigerate. Stable for 24 hours.
Use: This non-specific test is used to evaluate detect inflammatory states, autoimmune diseases, and plasma cell dyscrasias.
Test Code: RL93
Synonyms: Testosterone-binding Globulin
CPT Code: 84270
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature

Reference Range:
Male: 20-49 years: 16.5 - 55.9 ng/ml
> 49 years: 19.3 – 76.4 ng/ml
Female: 20-49 years: 24.6 - 122.0 ng/ml
> 49 years: 17.3- 125.0 ng/ml

Use: The sex hormone binding globulin (SHBG) test may be used to help evaluate men for low testosterone and women for excess testosterone production. It may be ordered in conjunction with other tests to evaluate the status of a person's sex hormones.
Test Code: 1162
CPT Code: 86235
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: SS-A is extractable nucleoprotein complexes found in the nucleus and/or cytoplasm of substrate cells. Aids in the diagnosis of Sjögren's syndrome (especially with vasculitis) and lupus patients with Sjögren's overlap syndrome.
Test Code: 1163
CPT Code: 86235
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.

Collection: Transfer separated serum or plasma to a plastic transport tube. Optimal sampling time after dosage is two to six hours. Optimal resampling time after change in dosage is six hours.

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: SS-B are extractable nucleoprotein complexes found in the nucleus and/or cytoplasm of substrate cells. Aids in the diagnosis of Sjögren's syndrome (especially with vasculitis) and lupus patients with Sjögren's overlap syndrome.
Test Code: 1159
Synonyms: Sm antibodies
CPT Code: 86225; 86235
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube.

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Anti-Sm is highly specific for SLE. Sm is an extractable nucleoprotein complexes found in the nucleus and/or cytoplasm of substrate cells.
Test Code: RL05
CPT Code: 84295
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, or green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection. Label specimen as serum.

Storage and Stability: Maintain at Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Electrolyte, acid-base balance; water balance; water intoxication; diagnose dehydration.
Test Code: 1115
Synonyms: Soluble transferrin receptor
CPT Code: 84238
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells and transfer to a plastic transport tube.
Storage and Stability: Refrigerate

Use: Measurement of sTfR is used to diagnose iron deficiency in individuals with chronic disease (inflammatory diseases, infections, malignancies), many of whom are anemic.
Test Code: RH18
Synonyms: Thyroid Hormone-binding Ratio (THBR), T3 Uptake
CPT Code: 84479
Specimen: Serum
Volume: 2 mL (adult), 0.8 mL (pediatric)
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Thyroid function test for the diagnosis of hypothyroidism or hyperthyroidism, used with thyroxine (T4) or equivalent to provide free T4 index, FTI. An indirect measure of binding protein, the T3 uptake reflects available binding sites (i.e., reflects TBG). T3 uptake is not a measurement of serum T3. It should never be used alone; rather, its usual application is use with thyroxine (T4).
Test Code: RL92
CPT Code: 84403
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Testosterone testing is used to evaluate androgen excess or deficiency related to gonadal function, adrenal function, or tumor activity. Testosterone levels may be helpful in men for the diagnosis of hypogonadism, hypopituitarism, Klinefelter syndrome, and impotence (low values). Testosterone levels may be requested in women to investigate the cause of hirsutism, anovulation, amenorrhea, virilization, masculinizing tumors of the ovary, tumors of the adrenal cortices, and congenital adrenal hyperplasia (high values). Testosterone levels in children may be helpful to investigate issues related to puberty and development as well as the aforementioned.
Test Code: RL94, RL95 (Percent)
CPT Code: 84402
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate hirsutism and masculinization in women; evaluate testicular function in clinical states where the testosterone binding proteins may be altered (obesity, cirrhosis, thyroid disorders).
Test Code: 1116
Synonyms: Aminophylline, Blood; Elixophyllin® Elixir; Theo-24®; Theo-Dur®; Theochron™; Theolair™; Uniphyl®
CPT Code: 80198
Specimen: Serum or plasma
Volume: 2 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Trough: immediately prior to next dose; after change in dose: children: two days, adults: one to two days.

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: To monitor levels of theophylline, a drug prescribed for bronchial asthma for chronic obstructive pulmonary disease, and for newborn apnea.
Test Code: RH16
Synonyms: Antithyroglobulin Antibody
CPT Code: 86800
Specimen: Serum
Volume: 2 mL
Container: Red-top tube, gel-barrier tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Stable for 14 days.
Use: Detect and confirm autoimmune thyroiditis, Hashimoto thyroiditis
Test Code: RL90
Synonyms: Tetraiodothyronine
CPT Code: 84436
Specimen: Serum
Volume: 2 mL (adult), 0.8 mL (pediatric)
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Thyroid function test. Used to diagnose T4 toxicosis.
Test Code: RH18
Synonyms: T3 Uptake
CPT Code: 84479
Specimen: Serum
Volume: 1 ml
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate

Room temperature: 14 days
Refrigerated: 14 days
Frozen: 14 days
Freeze/thaw cycles: Stable x3

Use:

Thyroid function test for the diagnosis of hypothyroidism or hyperthyroidism, used with thyroxine (T4) or equivalent to provide free T4 index, FTI. T3 uptake is not a measurement of serum T3. It should never be used alone; rather, its usual application is use with thyroxine (T4).
Instructions: Must be ordered with UIBC (1126) and Iron, total (RL74)
Test Code: 1019
Synonyms: Transferrin Saturation
CPT Code: 83540; 83550
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube or, green-top (heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate. Stable for 14 days.
Use: It is most frequently used along with a serum iron test to evaluate people suspected of having either iron deficiency or iron overload.
Test Code: 1081 (Trough), 1117 (Peak)
Synonyms: AK-Tob™, Nebcin®, TOBI®, Tobrex®
CPT Code: 80200
Specimen: Serum or plasma
Volume: 2 mL

Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Both peak and trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose. Peak samples should be drawn 60 minutes after an I.M. injection, 30 minutes after the end of a 30-minute I.V. infusion or immediately after a 60-minute I.V. infusion.

Storage and Stability: Room Temperature
Use: To measure and monitor the level of Tobramycin. Tobramycin is administered to treat serious infections caused by aerobic gram-negative bacilli.
Test Code: RL17
CPT Code: 82247
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel barrier tube or green-top (lithium heparin) tube
Collection: Separate serum or plasma from cells within 45 minutes of collection
Storage and Stability: Room Temperature

Room Temperature: 3 Days
Refrigerated: 3 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x2

Use: A bilirubin test is used to detect an increased level in the blood. It may be used to help determine the cause of jaundice and/or help diagnose conditions such as liver disease, hemolytic anemia, and blockage of the bile ducts.
Test Code: RL97
CPT Code: 82672
Specimen: Serum or plasma
Volume: 5 mL
Container: Red-top tube, gel barrier tube, or green-top (heparin) tube
Collection: If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Refrigerate

Room Temperature: 3 Days
Refrigerated: 7 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate for ovarian estrogen producing tumor in the premenarcheal and postmenopausal female; evaluate estrogen excess in males. Estrogen analysis may be helpful in establishing time of ovulation and optimal time for conception. Serial samples must be collected over several days to evaluate baseline and peak total estrogen levels.
Test Code: RL89
Synonyms: Human Chorionic Gonadotropin, β-Subunit, quantitative
CPT Code: 84702
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Quantitative hCG testing, often called beta hCG (β-hCG), measures the amount of hCG present in the blood. This test can be used for the early detection of and on-going monitoring of pregnancy. Determine the presence of hCG in patients with gestational trophoblastic disease; evaluate and monitor male patients with testicular tumors; follow up molar pregnancy. The quantitative hCG assay should be used for nonroutine detection of hCG (e.g, ectopic pregnancy (along with progesterone testing), threatened abortions, miscarriages, or very early pregnancy).
Test Code: 1118
Synonyms: Immunoglobulin E, Total
CPT Code: 82785
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 2 Days
Refrigerated: 7 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate immunoglobulin status may be used to screen for and detect allergic diseases. It may be ordered by itself, before, or along with allergen-specific IgE tests – depending upon whether or not a person or doctor has identified potential substances to which the person may be allergic. Normal IgE levels do not exclude allergic phenomena.
Test Code: RL10
CPT Code: 84155
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Gel-barrier tube, transport tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: Separate serum or plasma from cells within four hours of collection.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate nutritional status, and may be used to screen for and help diagnose kidney disease or liver disease, for example.
Test Code: 1119
Synonyms: Toxoplasmosis Antibodies
CPT Code: 86777
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube

Storage and Stability: Refrigerate. Specimen is stable for two days at room temperature and for seven days refrigerated. For storage longer than seven days, freeze the specimen.

Use: Support the diagnosis of toxoplasmosis; document past exposure and/or immunity to Toxoplasma gondii.
Test Code: 1120
Synonyms: Toxoplasmosis Acute Antibodies
CPT Code: 86778
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Storage and Stability: Refrigerate. Specimen is stable for two days at room temperature or refrigerated. For storage longer than two days, freeze the specimen.
Use: Support the diagnosis of toxoplasmosis
Test Code: RH14
Synonyms: Antimicrosomal Antibody, Thyroid Peroxidase (TPO) Antibodies, Antithyroid Microsomal Antibody
CPT Code: 86376
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature. Stable for 14 days.
Use: This test is to diagnose an autoimmune thyroid disease and to distinguish it from other forms of thyroid dysfunction.
Test Code: 1121
Synonyms: Siderophilin
CPT Code: 84466
Specimen: Serum (preferred) or plasma
Volume: 1 mL
Container: Gel-barrier tube, red-top tube, or green-top (heparin) tube; do not use EDTA plasma.
Collection: Fasting specimen is preferred.
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Increased in iron deficiency anemia. It is decreased in chronic inflammatory states, hereditary atransferrinemia, some instances of acquired liver disease, neoplasia, and renal disease. Transferrin is an index of nutritional status.
Test Code: RL20
CPT Code: 84478
Specimen: Serum (preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube. Do not use glycerinated Vacutainer® tubes.
Collection: Separate serum or plasma from cells within 45 minutes of collection.

Limitations: Some women on estrogens and high estrogen oral contraceptives have an increase of triglyceride. Increase occur with pregnancy, similar to those with oral contraceptives. The most common cause of triglyceride increase is inadequate patient fasting. Hypertriglyceridemia is associated with use of thiazide diuretics and β-adrenergic blocking agents.

Storage and Stability: Room Temperature

Room Temperature: 7 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Blood tests for triglycerides are usually part of a lipid profile used to identify the risk of developing heart disease. As part of a lipid profile, it may be used to monitor people who have risk factors for heart disease, those who have had a heart attack, or those who are being treated for high lipid and/or high triglyceride levels.
Test Code: RH10
Synonyms: T3, Total
CPT Code: 84480
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Thyroid function which is particularly useful in the diagnosis of T3 thyrotoxicosis and may be ordered to help monitor treatment of a person with a known thyroid disorder. It is increased in and occasionally helpful for confirmation of diagnosis of conventional hyperthyroidism, in which commonly both T3 and T4 levels are increased. T3 is needed in patients with clinical evidence for hyperthyroidism, in whom the usual thyroid profile is normal or borderline.
Test Code: 1032
Synonyms: Cardiac Troponin I, cTnI
CPT Code: 84484
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Refrigerate

Room Temperature: 2 Days
Refrigerated: 2 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Troponin tests are primarily ordered to help diagnose a heart attack and rule out other conditions with similar signs and symptoms. Troponin I and troponin T are proteins found in heart muscle and are released into the blood when there is damage to the heart. Increased troponin levels should not be used by themselves to diagnose or rule out a heart attack. A physical exam, clinical history, and ECG are also important.
Test Code: RL18
Synonyms: Thyrotropin, Thyroid-stimulating Hormone
CPT Code: 84443
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: The thyroid-stimulating hormone (TSH) test is often the test of choice for evaluating thyroid function and/or symptoms of a thyroid disorder, including hyperthyroidism or hypothyroidism. TSH is high in primary hypothyroidism. Low TSH occurs in hyperthyroidism. Evaluation of therapy in hypothyroid patients receiving various thyroid hormone preparations: Low values are found in states of excessive thyroid replacement. Normal result on a sensitive TSH assay is acceptable evidence of adequate thyroid replacement.
Test Code: 1056
Synonyms: Thyroid Cascade
CPT Code: 84443; If reflex testing is performed, additional CPT codes (i.e., 84439, 84481, 86376)
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel-barrier tube
Collection: If red-top tube is used, transfer separated serum to a plastic transport tube.
Storage and Stability: Room temperature

Use: An appropriate diagnosis for common adult thyroid disorders. If the TSH result is normal, a euthyroid status is assumed and testing stops. Additional testing is performed only if the initial TSH result is abnormally high or low. This profile is not intended for use in pediatric patients.
Test Code: RL76
Synonyms: Estriol, E3, Pregnancy, Estriol
CPT Code: 82677
Specimen: Serum
Volume: 1 mL
Container: Red-top tube or gel-barrier tube

Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube. All specimens should be drawn at the same time of day to allow comparison of values.

Storage and Stability: Refrigerate

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Evaluate fetal distress and placental function in the management of patients facing complications such as preëclampsia, fetal growth retardation, diabetes, Rh immunization, choriocarcinoma, and hydatidiform mole. May be elevated in hydrops fetalis in the presence of a dying fetus. May be low in the presence of a living anencephalic fetus. Unconjugated estriol is often measured in the 15th to 20th week of gestation as part of the triple/quad screen.
Test Code: 1126
Synonyms: Fe and TIBC; TIBC and Iron; Total Iron-binding Capacity (TIBC); Transferrin Saturation; Unsaturated Iron-binding Capacity (UIBC)
CPT Code: 83550
Specimen: Serum (preferred) or plasma (lithium heparin only). EDTA plasma causes decreased results.
Volume: 2 mL
Container: Gel-barrier tube, transport tube, or green-top (lithium heparin) tube, do not use EDTA or oxalate anticoagulants.
Collection: Separate serum or plasma from cells within 45 minutes of collection
Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Total iron-binding capacity (TIBC) is most frequently used along with a serum iron test to evaluate people suspected of having either iron deficiency (anemia) or iron overload (hemochromatosis). These two tests are used to calculate the transferrin saturation, a more useful indicator of iron status than just iron or TIBC al one. Decrease in iron level after performance of Schilling supports the diagnosis of vitamin B12 deficiency, vide infra. Evaluate iron poisoning (toxicity) and overload in renal dialysis patients, or patients with transfusion dependent anemias.
Test Code: RL43
Synonyms: UA; Urate
CPT Code: 84550
Specimen: Serum (preferred) or plasma
Volume: 1 mL
Container: Red-top tube, gel barrier tube, green-top (lithium heparin) tube, or lavender top (EDTA) tube.
Collection: Separate serum or plasma from cells within 45 minutes of collection.
Storage and Stability: Refrigerate

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: The uric acid blood test is useful in the diagnosis of gout. The test is also used to monitor uric acid levels in people undergoing chemotherapy or radiation treatment for cancer. Rapid cell turnover from such treatment can result in an increased uric acid level.
Test Code: UA01, UA02 (w/reflex)
CPT Code: 81001
Specimen: Urine
Volume: 10 mL
Container: Routine urinalysis tube or container, BD urine transport tube, or sterile urine cup
Collection: A voided specimen is usually suitable. If the specimen is likely to be contaminated, a clean catch midstream specimen is desirable.
Storage and Stability: Refrigerate

Use: The test is used to detect abnormalities of urine, diagnose and manage renal disease, urinary tract infection, urinary trace neoplasms, systemic disease, and inflammatory or neoplastic diseases adjacent to the urinary trace.
Test Code: R002
Specimen: Culture, Urine, Comprehensive
CPT Code: 87086
Specimen: Urine
Volume: To fill line on Vacutainer® gray-top urine culture transport tube
Container: Vacutainer® gray-top urine culture transport tube with preservative
Collection: Clean-catch midstream urine collection

This method helps protect the urine sample from germs that are normally found on the penis or vagina.

Wash your hands before collecting the urine.

If the collection container has a lid, remove it carefully and set it down with the inner surface up.

Clean the area around your penis or vagina.

A man should retract the foreskin, if present, and clean the head of his penis thoroughly with medicated towelettes or swabs.

A woman should spread open the folds of skin around her vagina with one hand, then use her other hand to clean the area around her vagina and urethra thoroughly with medicated towelettes or swabs. She should wipe the area from front to back to avoid spreading bacteria to the vagina that is normally found around the anus.

Begin urinating into the toilet or urinal. A woman should continue holding apart the folds of skin around the vagina while she is urinating.

After the urine has flowed for several seconds, place the collection container in the stream and collect about 60 mL (2 fl oz) of this "midstream" urine without stopping the flow.

Do not touch the rim of the container to your genital area.

Do not get toilet paper, hair, feces, or menstrual blood in the urine sample.

Finish urinating into the toilet or urinal.

Carefully replace the lid on the container. Wash your hands. Return the urine sample to the lab. If you are collecting the urine at home and cannot get it to the lab within an hour, refrigerate the sample. It can be refrigerated for up to 24 hours. Follow the instructions from your lab.

Storage and Stability: Refrigerate

Use: The test is used to detect abnormalities of urine, diagnose and manage renal disease, urinary tract infection, urinary trace neoplasms, systemic disease, and inflammatory or neoplastic diseases adjacent to the urinary trace.
Test Code: RB04
Synonyms: Depacon®, Depakene®, Depakote®, Stavzor™, Valproate
CPT Code: 80164
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Collection: Transfer separated serum or plasma to a plastic transport tube. Oral: peak: one to four hours after dose (influenced by meals); trough: immediately prior to next dose (possibly more useful than peak values).

Storage and Stability: Room Temperature

Room Temperature: 14 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: The valproic acid test is used to measure and monitor the amount of valproic acid in the blood and determine whether the drug concentration is within the therapeutic range.
Test Code: (Peak) 1127; (Through) 1135
Synonyms: Vancocin
CPT Code: 80202
Specimen: Serum or plasma
Volume: 2 mL
Container: Red-top tube or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.

Collection: Transfer separated serum or plasma to a plastic transport tube. Both peak and trough concentrations should be monitored. The trough sample is drawn immediately prior to the next dose.

Storage and Stability: Refrigerate

Room Temperature: 3 Days
Refrigerated: 14 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: Monitor levels of the antimicrobial drug vancomycin in the blood.

Because the goal is to administer the vancomycin such that a minimally effective concentration is always maintained in the blood, measurement of blood levels is usually timed to reflect the trough and, sometimes peak, to evaluate the adequacy of dosing and clearance of the drug from the body. Trough levels are collected just prior to a person's next vancomycin dose. Peak levels are collected 1 to 2 hours after the completion of the intravenous vancomycin dose.

The trough and sometimes peak values are used by clinical pharmacists and health practitioners to calculate rates of absorption and clearance of the drug. These results are then used to determine the appropriate amount of drug and the appropriate timing between doses to assure that the blood concentration remains in the therapeutic range.

Test Code: 0341
Synonyms: 3-Methoxy-4-Hydroxymandelic Acid, VMA
CPT Code: 84585
Specimen: Urine
Volume: 5 mL
Container: Plastic urine container, no preservative.

Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.

Patient Preperation: Patient should avoid salicylates, caffeine, phenothiazine, and antihypertension agents. Also coffee, tea, chocolate, fruit (especially bananas and any vanilla-containing substances for 72 hours prior to collection).

Storage and Stability: Room Temperature

Use: Pediatric testing for the evaluation of hypertension; diagnose and follow up neuroblastoma, ganglioneuroma, and ganglioneuroblastoma. Most neuroblastoma patients excrete excess HVA in 24-hour collections.
Test Code: 1169
Synonyms: B6; B6, Vitamin; PLP; Pyridoxal-5-Phosphate; Pyridoxine
CPT Code: 84207
Specimen: Plasma, protected from light
Volume: 2 mL
Container: Lavender-top (EDTA) tube or green-top (heparin) tube
Collection: Draw blood. Immediately separate plasma from red cells. Protect specimen from light.
Storage and Stability: Refrigerated or room temperature, protect from light.

Room Temperature: 3 Days
Refrigerated: 14 Days
Frozen: 16 Days
Freeze/Thaw Cycles: Stable x3

Use: Detect vitamin B6 deficiency.
Test Code: RB08
Synonyms: Cobalamin, True
CPT Code: 82607
Specimen: Serum
Volume: 2 mL
Container: Red-top tube or gel barrier tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Patient Preparation: Fasting specimen preferred; must draw before Schilling test, transfusions or B12 therapy is started.
Storage and Stability: Room Temperature

Room Temperature: 7 Days
Refrigerated: 7 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: • Detect B12 deficiency as in pernicious anemia;
• Diagnose folic acid deficiency; evaluate hypersegmentation of granulocyte nuclei;
• Follow up MCV >100;
• Diagnose macrocytic anemia;
• Diagnose megaloblastic anemia;
• Evaluate alcoholism, prenatal care;
• Evaluate malabsorption, neurological disorders, or the elevation of B12 as seen in liver cell damage or myeloid leukemia
Test Code: 1145
Synonyms: Calcitriol; 1,25(OH) Vitamin D; 1,25-Dihydroxy Vitamin D; 1,25-Dihydroxycholecalciferol; Vitamin D, 1,25-Dihydroxy
CPT Code: 82652
Specimen: Serum (Preferred) or plasma
Volume: 2 mL
Container: : Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: If a red-top tube is used, transfer separated serum to a plastic transport tube.
Patient Preparation: Fasting specimen preferred; must draw before Schilling test, transfusions or B12 therapy is started.
Storage and Stability: Room Temperature

Room Temperature: 7 Days
Refrigerated: 7 Days
Frozen: 14 Days
Freeze/Thaw Cycles: Stable x3

Use: • Detect B12 deficiency as in pernicious anemia;
• Diagnose folic acid deficiency; evaluate hypersegmentation of granulocyte nuclei;
• Follow up MCV >100;
• Diagnose macrocytic anemia;
• Diagnose megaloblastic anemia;
• Evaluate alcoholism, prenatal care;
• Evaluate malabsorption, neurological disorders, or the elevation of B12 as seen in liver cell damage or myeloid leukemia
Test Code: 1145
Synonyms: Calcitriol; 1,25(OH) Vitamin D; 1,25-Dihydroxy Vitamin D; 1,25-Dihydroxycholecalciferol; Vitamin D, 1,25-Dihydroxy
CPT Code: 82652
Specimen: Serum (Preferred) or plasma
Volume: 2 mL
Container: Red-top tube, gel-barrier tube, green-top (heparin) tube, or lavender-top (EDTA) tube
Collection: If tube other than a gel-barrier tube is used, transfer separated serum or plasma to a plastic transport tube.
Storage and Stability: Room Temperature

Room Temperature: 10 Days
Refrigerated: 10 Days
Frozen: 10 Days
Freeze/Thaw Cycles: Stable x3

Use: This test is ordered when calcium is high or the patient has a disease leading to excess production of vitamin D. Calcitriol assessment may also be beneficial in patients with chronic kidney failure or early-onset rickets or a family history of rickets. Calcitriol may also be helpful in the diagnosis of parathyroid function disorders.
Test Code: 0337
Synonyms: Xanthurenate
CPT Code: 83919
Specimen: Urine
Volume: 2 mL
Container: Plastic urine container. No preservative.

Collection: Label container with patient's name, date, and time. For 24-hour urine, transfer 5 mL aliquot from well-mixed refrigerated 24-hour container. Measure and record total urine volume and collection time interval on cup/requisition form.

Storage and Stability: Ambient temperature, Refrigerated
Use: Vitamin B6 functional test


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